Results 31 to 40 of about 35,966 (131)
Anemoside B4 inhibits enterovirus 71 propagation in mice through upregulating 14-3-3 expression and type I interferon responses. [PDF]
Acta Pharmacol Sin, 2022 Enterovirus 71 (EV71) is the major pathogens of human hand, foot, and mouth disease (HFMD). EV71 efficiently escapes innate immunity responses of the host to cause infection. At present, no effective antiviral drugs for EV71 are available.
Kang NX +9 more
europepmc +2 more sources
Anemoside B4 inhibits SARS-CoV-2 replication in vitro and in vivo. [PDF]
Chin Herb MedAnemoside B4 (AB4), the most abundant triterpenoidal saponin isolated from Pulsatilla chinensis, inhibited influenza virus FM1 or Klebsiella pneumoniae-induced pneumonia. However, the anti-SARS-CoV-2 effect of AB4 has not been unraveled. Therefore, this study aimed to determine the antiviral activity and potential mechanism of AB4 in inhibiting human ...
Xiao M +9 more
europepmc +3 more sources
Anemoside B4 alleviates arthritis pain via suppressing ferroptosis-mediated inflammation. [PDF]
J Cell Mol MedAbstractChronic pain is the key manifestations of rheumatoid arthritis. Neuroinflammation in the spinal cord drives central sensitization and chronic pain. Ferroptosis has potentially important roles in the occurrence of neuroinflammation and chronic pain.
Guo C +8 more
europepmc +3 more sources
Anemoside B4 sensitizes human colorectal cancer to fluorouracil-based chemotherapy through src-mediated cell apoptosis. [PDF]
Aging (Albany NY), 2021 Currently, 5-Fluorouracil (5-FU) based chemotherapy is the primary option for colorectal cancer after surgery, whereas chemotherapy resistance related mortality is observed in a large proportion of patients. Anemoside B4 (AB4) is a triterpene saponin, which exhibits a considerable activity in oncotherapy.
He X +9 more
europepmc +3 more sources
Effects of anemoside B4 on pharmacokinetics of florfenicol and mRNA expression of CXR, MDR1, CYP3A37 and UGT1E in broilers. [PDF]
J Vet Med Sci, 2019 Pulsatillae radix, a traditional Chinese medicine (TCM), is often used in combination with florfenicol for treatment of intestinal infection in Chinese veterinary clinics. Anemoside B4 (AB4) is the major effective saponin in Pulsatillae radix. This study aimed to investigate whether the pharmacokinetics of florfenicol in broilers was affected by the ...
Li S +7 more
europepmc +4 more sources
, 2022 The study was conducted to evaluate the effects of Anemoside B4 on diarrhea incidence, serum indices, and fecal microbial of suckling calves. Sixty newborn Chinese Holstein calves with similar body weight (43.7 ± 3.9 kg) were randomly divided into four ...
Tao Ma (88669) +6 more
core +1 more source
, 2022 The study was conducted to evaluate the effects of Anemoside B4 on diarrhea incidence, serum indices, and fecal microbial of suckling calves. Sixty newborn Chinese Holstein calves with similar body weight (43.7 ± 3.9 kg) were randomly divided into four ...
Tao Ma (88669) +6 more
core +1 more source
Therapeutic potential of triterpenoid saponin anemoside B4 from Pulsatilla chinensis
Pharmacological Research, 2020 Pulsatilla Decoction (Bai-Tou-Weng-Tang) has been used medically in China for thousands of years for the treatment of diseases caused by bacteria. In recent decades, Pulsatilla Decoction is becoming a well-known formula prescription used for the treatment of ulcerative colitis in traditional Chinese medicine.
Yan-Hong, Li +4 more
openaire +2 more sources
Anemoside B4 alleviates neuropathic pain through inhibiting inflammation
, 2022 Abstract Research background: Neuropathic pain (NP), which is caused by nerve injury or other diseases damages patients’ life quality seriously. Anemoside B4 (AB4) is the active component of triterpenoid saponins in traditional Chinese medicine Pulsatilla, with prominent effects of anti-inflammation and analgesia.
Minghong Zhao +7 more
openaire +1 more source
, 2021 supplement metarial for "Effect of anemoside B4 on milk whey in clinical mastitis-affected cows elucidated using tandem mass tag (TMT)-based quantitative proteomics"THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
张, 钺 (via Mendeley Data)
core +1 more source