Results 71 to 80 of about 7,817,858 (363)

A novel multivariate STeady-state index during general ANesthesia (STAN) [PDF]

, 2017
The assessment of the adequacy of general anesthesia for surgery, namely the nociception/anti-nociception balance, has received wide attention from the scientific community. Monitoring systems based on the frontal EEG/EMG, or autonomic state reactions (e.
A Albertin, A Castro, A Castro, A Cividjian, A Ekman, AM Zbinden, AM Zbinden, Ana Castro, B Rehberg, Catarina S. Nunes, CF Minto, DI Sessler, E Farag, Fernando Gomes de Almeida, GA Mashour, H Storm, L Barvais, L Sörnmo, M Bahoura, M Huiku, M Jeanne, M Rantanen, MPJ Paloheimo, MT Rovere La, Pedro Amorim, PS Myles, S Karri, S Mallat, SD Greenwald, T Jiang, TG Monk, TW Bouillon, TW Schnider, WS Cleveland, Z Szabó   +34 more
core   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Effect of transcutaneous electrical acupoint stimulation on the quality of postoperative recovery: a meta-analysis

BMC Anesthesiology
Background The purpose of the present study was to systematically delve into the efficacy and safety of transcutaneous electrical acupoint stimulation (TEAS) on the quality of recovery after general anesthesia.
Meng Zhang, Huanhuan Zhang, Pan Li, Jianli Li   +3 more
doaj   +1 more source

A lung rescue team improves survival in obesity with acute respiratory distress syndrome

Critical Care, 2020
Background Limited data exist regarding ventilation in patients with class III obesity [body mass index (BMI) > 40 kg/m2] and acute respiratory distress syndrome (ARDS). The aim of the present study was to determine whether an individualized titration of
Gaetano Florio, Matteo Ferrari, Edward A. Bittner, Roberta De Santis Santiago, Massimiliano Pirrone, Jacopo Fumagalli, Maddalena Teggia Droghi, Cristina Mietto, Riccardo Pinciroli, Sheri Berg, Aranya Bagchi, Kenneth Shelton, Alexander Kuo, Yvonne Lai, Abraham Sonny, Peggy Lai, Kathryn Hibbert, Jean Kwo, Richard M. Pino, Jeanine Wiener-Kronish, Marcelo B. P. Amato, Pankaj Arora, Robert M. Kacmarek, Lorenzo Berra, For the investigators of the lung rescue team   +24 more
doaj   +1 more source

Reduced neural activity during volatile anesthesia compared to TIVA: evidence from a novel EEG signal processing analysis [PDF]

arXiv, 2020
Post-operative cognitive decline is a well-known phenomenon and of crucial importance especially in the elderly. General anesthesia can be accomplished by inhalation-based (volatile) or total intravenous anesthesia (TIVA). While their effects on post-operative symptoms have been investigated, little is known about their influence on brain ...
arxiv  

Radical pairs may play a role in microtubule reorganization [PDF]

arXiv, 2021
The exact mechanism behind general anesthesia remains an open question in neuroscience. It has been proposed that anesthetics selectively prevent consciousness and memory via acting on microtubules (MTs). It is known that the magnetic field modulates MT organization. A recent study shows that a radical pair model can explain the isotope effect in xenon-
arxiv  

Adverse Events and Factors Associated with Potentially Avoidable Use of General Anesthesia in Cesarean Deliveries

Anesthesiology, 2019
What We Already Know about This Topic Neuraxial anesthesia is recommended in lieu of general anesthesia for cesarean deliveries The association of general anesthesia without a clinical indication with adverse events in cesarean deliveries remains poorly ...
J. Guglielminotti, R. Landau, Guohua Li
semanticscholar   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Dexmedetomidine inhibits the lipopolysaccharide‐stimulated inflammatory response in microglia through the pathway involving TLR4 and NF‐κB

Kaohsiung Journal of Medical Sciences, 2019
To investigate the effects of dexmedetomidine (DEX) on lipopolysaccharide (LPS)‐induced neuroinflammation in BV2 microglia. BV2 microglial cells were treated with various concentrations of DEX (0, 1, 10, and 100 ng/mL) for 1 hour, and then incubated in ...
Xue‐Yue Zhou, Jing Liu, Zhi‐Peng Xu, Qiang Fu, Pei‐Qi Wang, Hong Zhang   +5 more
doaj   +1 more source

Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

Journal of Neuroinflammation, 2019
Background It is widely accepted that mitochondria have a direct impact on neuronal function and survival. Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolysaccharide (LPS)-induced memory ...
Weixing Zhao, Zhipeng Xu, Jiangbei Cao, Qiang Fu, Yishuang Wu, Xiaoying Zhang, Yue Long, Xuan Zhang, Yitian Yang, Yunfeng Li, Weidong Mi   +10 more
doaj   +1 more source