Results 61 to 70 of about 616,628 (329)

Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]

, 2015
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter, Dettoraki, Maria, Giannis, Athanassios, Glynos, Constantinos, Karavana, Vassiliki, Kotsikoris, Vasilis, Loverdos, Konstantinos, Magkou, Christina, Papapetropoulos, Andreas, Pavlidou, Athanasia, Perlikos, Fotis, Theocharis, Stamatios E, Topouzis, Stavros, Toumpanakis, Dimitris, Vassilakopoulos, Theodoros, Zhou, Zongmin   +15 more
core   +2 more sources

Visible, Safe and Certain Endotracheal Intubation Using Endoscope System and Inhalation Anesthesia for Rats

Journal of Veterinary Medical Science, 2014
Anesthesia strongly influences laboratory animals, and it can also greatly affect the experimental data. Rats rank only second to mice in the number used in research fields, such as organ transplantation, regenerative medicine and imaging.
Ken-ichi Konno, Y. Shiotani, N. Itano, Teppei Ogawa, Mika Hatakeyama, K. Shioya, N. Kasai   +6 more
semanticscholar   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

The Advantages of Low-Flow Inhalational Anesthesia

Общая реаниматология, 2005
The paper deals with the economical and ecological use of inhalation anesthetics in low-flow anesthesia (LFA, 1—0.5 l/ min) and high-flow anesthesia (HFA, more than 2—6 l/min).
P. Torok, P. Candik, E. Drbjakova, I. Lakatos, P. Toya, J. Salantay, P. Cicatko, J. Gyoriova, M. Majek   +8 more
doaj   +1 more source

Inhalation anesthesia and stress in children with oncological pathology

Zdorovʹe Rebenka, 2022
Background. Children with cancer undergo many ­operations and procedures that require anesthesia in the acute phase of the disease or during remission. An integral element of a safe anesthesia plan is the consideration of direct tumor effects.
V.I. Snisar, D.V. Myronov
doaj   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

Advanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro, María Sancho‐Albero, Silvia Miguel, Andrea Mosseri, Felipe Hornos, Rafael Contreras‐Montoya, Jose L. Hueso, Jesus Santamaria   +7 more
wiley   +1 more source

Depth of Anesthesia Determination by using Bispectral Index in Patients underwent Inhalation or Total Intravenous General Anesthesia

مجله دانشکده پزشکی اصفهان, 2008
BACKGROUND: Bispectral index (BIS) is a new method for determination depth of anesthesia. In most of our operating rooms depth of anesthesia is measured according to clinical features; however, it has not enough accuracy.
Gholam Reza Kalili, Parvin Sajedi, Forough Afsharyzadeh   +2 more
doaj  

Mouse and Rat Anesthesia and Analgesia

Current Protocols
Anesthesia and analgesia play pivotal roles in ethically and humanely using animal models in research, especially concerning mice and rats. These rodent species, extensively utilized in scientific investigations due to their genetic resemblance to humans,
Sang Su Oh, Heather L Narver
semanticscholar   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

The unique challenges of Brugada syndrome in spinal deformity surgery

Interdisciplinary Neurosurgery, 2021
Brugada Syndrome (BrS) is a genetic condition associated with ventricular fibrillation and sudden cardiac death. In BrS, several pharmacological agents may increase the risk for arrhythmia and total intravenous anesthesia with propofol (TIVA) may be ...
F.G. Sigmundsson, J. Kuchalik, S. Fadl, M. Holy, A. Joelson   +4 more
doaj   +1 more source