Results 81 to 90 of about 123,027 (267)

The Locus Coeruleus Modulates Intravenous General Anesthesia of Zebrafish via a Cooperative Mechanism

Cell Reports, 2018
Summary: How general anesthesia causes loss of consciousness has been a mystery for decades. It is generally thought that arousal-related brain nuclei, including the locus coeruleus (LC), are involved.
Wen-jie Du, Rong-wei Zhang, Jia Li, Bai-bing Zhang, Xiao-lan Peng, Song Cao, Jie Yuan, Cheng-dong Yuan, Tian Yu, Jiu-lin Du   +9 more
doaj  

Comparison of intraoperative neurophysiological monitoring between propofol and remimazolam during total intravenous anesthesia in the cervical spine surgery: a prospective, double-blind, randomized controlled trial [PDF]

Korean Journal of Anesthesiology
Background Although total intravenous anesthesia (TIVA) with propofol and remifentanil is frequently used to optimize intraoperative neurophysiological monitoring (IONM), the exact effect of remimazolam on IONM remains unknown.
Myoung Hwa Kim, Jinyoung Park, Yoon Ghil Park, Yong Eun Cho, Dawoon Kim, Dong Jun Lee, Kyu Wan Kwak, Jongyun Lee, Dong Woo Han   +8 more
doaj   +1 more source

The Modeling and Quantification of Rhythmic to Non-rhythmic Phenomenon in Electrocardiography during Anesthesia [PDF]

arXiv, 2015
Variations of instantaneous heart rate appears regularly oscillatory in deeper levels of anesthesia and less regular in lighter levels of anesthesia. It is impossible to observe this "rhythmic-to-non-rhythmic" phenomenon from raw electrocardiography waveform in current standard anesthesia monitors. To explore the possible clinical value, I proposed the
arxiv  

Wearable Systems of Reconfigurable Microneedle Electrode Array for Subcutaneous Multiplexed Recording of Myoelectric and Electrochemical Signals

Advanced Science, EarlyView.
A reconfigurable microneedle electrode array integrated system is developed for minimally invasive and transdermal monitoring of subcutaneous electromyography, reactive oxygen species, and pH values. By assembling discrete thumbtack‐shaped microneedles into an array, the system enables multi‐parameter detection with single‐microneedle resolution.
Zhengjie Liu, Chuanjie Yao, Xingyuan Xu, Xinshuo Huang, Shuang Huang, Shantao Zheng, Tao Zhang, Yan Li, Fanmao Liu, Yuxiang Wu, Jing Liu, Hui‐jiuan Chen, Xi Xie   +12 more
wiley   +1 more source

Application of propofol-remifentanil intravenous general anesthesia combined with regional block in pediatric ophthalmic surgery

BMC Anesthesiology
Objective The aim of this study is to observe the anesthetic effect and safety of intravenous anesthesia without muscle relaxant with propofol-remifentanil combined with regional block under laryngeal mask airway in pediatric ophthalmologic surgery ...
Ming-Ying Li, Yu-Da Fei, Xiao-Xia Zhang, Tian-Wen Chen, Jie Li, Xiao-Li Sun, Zhen-Yuan Wang   +6 more
doaj   +1 more source

Clinical analysis of different anesthesia methods for pulmonary infection after perioperative operation

Journal of Infection and Public Health, 2021
The purpose is to explore the effect of different anesthesia methods on pulmonary infection after the operation. 120 patients who underwent surgery from January 2015 to August 2018 were selected in three groups: group A (n = 40), group B (n = 40), and ...
Qingqing Huang, Digui Weng, Jinqiang Yuan, Yagui Liang, Sanying Cai, Runnian Jiang   +5 more
doaj  

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidan Chen   +21 more
wiley   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Changes in echocardiographic indices and left ventricular strain values by two-dimensional speckle-tracking echocardiography following pre-anesthetic oral pimobendan administration compared with intravenous pimobendan in dogs

Frontiers in Veterinary Science
IntroductionThe effects of pre-anesthetic single-dose oral pimobendan during inhalational anesthesia, including the comparison with the effects of single intravenous pimobendan under anesthesia, remain unexplored. Therefore, this study aimed to determine
Yijin Jeong, Yijin Jeong, Bumseok Kim, Sung-Soo Kim, Kichang Lee, Hakyoung Yoon, Hakyoung Yoon   +6 more
doaj   +1 more source