Results 81 to 90 of about 1,112,203 (353)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Effect of Combined Oral Ferrotherapy with L-carnitine on Exercise Tolerance of Patients with Chronic Heart Failure with Reduced Ejection Fraction of Left Ventricle with Concomitant Iron Deficiency Anemia [PDF]

, 2019
According to numerous studies, a high prevalence of iron deficiency (ID) with anaemic syndrome and its association with mortality during chronic heart failure (CHF) have been revealed.
Ivanov, V. (Valerii), Kolesnyk, М. (Маriia)   +1 more
core   +3 more sources

Total Intravenous Anesthesia in Neurosurgery

Journal of Neuroanaesthesiology and Critical Care, 2018
In recent years, neurosurgical anesthesia has been rapidly evolving in the fields of pharmacotherapy and techniques to administer safe anesthesia. Intravenous (IV) anesthetic agents reduce both cerebral blood flow and intracranial pressure besides ...
Narmadhalakshmi Kannabiran, P. Bidkar
semanticscholar   +1 more source

Nitric Oxide‐Releasing Catheters with Phenol‐Amine Catalytic Coatings for Improved Anti‐Inflammatory Performance

Advanced Healthcare Materials, EarlyView.
Tannic acid‐selenocystamine (TA‐SeCA) nanocoating enables stable, sustained catalytic nitric oxide (NO) release on catheter surfaces. This one‐step phenol‐amine coating improves catheter functionality by enhancing endogenous NO production, supporting vascular function, and reducing inflammation.
Qingqing Fan, Shu Geng, Tanveer A. Tabish, Kang Lin, Yiyi Yin, Siti Nur Asyura Adzlan, Federico Mazur, Rona Chandrawati   +7 more
wiley   +1 more source

Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study [PDF]

, 2017
Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA),
Araujo, A. M., Campos, M. T., Machado, Humberto S., Nunes, Catarina S.   +3 more
core   +1 more source

Nanoscale Bupivacaine Formulations To Enhance the Duration and Safety of Intravenous Regional Anesthesia.

ACS Nano, 2018
Intravenous regional anesthesia (IVRA; Bier block) is commonly used to anesthetize an extremity for surgery. Limitations of the procedure include pain from the required tourniquet, the toxicity that can occur from systemic release of local anesthetics ...
C. Weldon, T. Ji, Minh T Nguyen, Alina Y. Rwei, Weiping Wang, Yi Hao, Chao Zhao, Manisha Mehta, Bruce Y Wang, Jonathan H. Tsui, R. Marini, D. Kohane   +11 more
semanticscholar   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Deep sedation in patients undergoing atrioventricular nodal reentry tachycardia ablation

Research in Cardiovascular Medicine, 2013
Background: General anesthesia and deep sedation can be used during cardiac EPS to relief pain and provide comfort and immobility, but many electrophysiologists avoid sedation for better arrhythmia induction. Objective: To determine anesthesia effects in
Amirfarjam Fazelifar, Ali Eskandari, Mohammadjafar Hashemi, Mostafa Alavi, Mohammadzia Totounchi, Azam Forghanian, Mahboubeh Zeighami, Zahra Emkanjoo, Majid Haghjoo   +8 more
doaj   +1 more source

Nurses\u27 Alumnae Association Bulletin, May 1956 [PDF]

, 1956
Alumnae Notes Anesthesiology at Jefferson Committee Reports Digest of Alumnae Meetings Graduation Awards - 1955 Marriages Necrology New Arrivals Physical Advances at Jefferson President\u27s Message School of Nursing Report Thomas A.
Edgar, Dorothy J, Heverly, Isabelle Kevel, Prevost, Mabel C, Rake, Paul F   +3 more
core   +1 more source

A snapshot of compliance with the sepsis six care bundle in two acute hospitals in the West Midlands, UK [PDF]

, 2019
The sepsis six care bundle has been adopted by hospitals in England and Wales for the management of patients with sepsis, with the aim of increasing survival when all elements of the bundle are achieved.
Frankling, Catriona, Gao, Fang, Melody, Teresa, Patel, Jaimin M., Sharif, Ben, Szakmany, Tamas, Yeung, Joyce   +6 more
core   +1 more source