Results 151 to 160 of about 5,515,945 (353)

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

open access: yesAdvanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao   +11 more
wiley   +1 more source

Long⁃term effects of deep brain stimulation for Parkinson's disease under local or general anesthesia

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To compare the efficacy of local anesthesia and general anesthesia of subthalamic nucleus deep brain stimulation (STN⁃DBS) for Parkinson's disease (PD).
Shu WANG   +11 more
doaj  

Phentolamine mesylate: It′s role as a reversal agent for unwarranted prolonged local analgesia

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2015
Administration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed.
Harpreet Singh Grover   +3 more
doaj   +1 more source

RECENT ADVANCES IN LOCAL ANESTHESIA

open access: yesInternational Journal of Advanced Research, 2019
Pain and anxiety are the two main reasons that contribute to the avoidance of dental care. Treating of such patients is stressful for the dentist which might ultimately results in the failure of the treatment, as regardless of practioner?s clinical skills, the dental treatment might become compromised without effective pain control system.
Dilip Kumar   +5 more
openaire   +3 more sources

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

open access: yesAdvanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung   +6 more
wiley   +1 more source

Cryo-EM structure of small-molecule agonist bound delta opioid receptor-Gi complex enables discovery of biased compound

open access: yesNature Communications
Delta opioid receptor (δOR) plays a pivotal role in modulating human sensation and emotion. It is an attractive target for drug discovery since, unlike Mu opioid receptor, it is associated with low risk of drug dependence.
Lin Cheng   +17 more
doaj   +1 more source

Kirigami‐Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A kirigami‐inspired breathable smart contact lens is reported for wireless monitoring of corneal hypoxia and microenvironment. The ultrathin (55 µm) and flexible sensing device enables digitalized, in situ and precise monitoring of dissolved oxygen, humidity, and temperature (R2 >0.98).
Jiaxue Zhu   +11 more
wiley   +1 more source

Deep learning with spatiotemporal consistency for nerve segmentation in ultrasound images [PDF]

open access: yesarXiv, 2017
Ultrasound-Guided Regional Anesthesia (UGRA) has been gaining importance in the last few years, offering numerous advantages over alternative methods of nerve localization (neurostimulation or paraesthesia). However, nerve detection is one of the most tasks that anaesthetists can encounter in the UGRA procedure.
arxiv  

EVALUATION OF THE EFFECTS OF ADDING KETAMINE TO MORPHINE IN PCIA AFTER ORTHOPEDIC SURGERY [PDF]

open access: yes
Background: Midazolam is the only clinically available water – soluble benzodiazepine has been reported to have an antinoceptive effect through neuroaxial pathway .
اخوان اکبری, قدرت   +4 more
core  

LOCAL ANESTHESIA IN GENERAL SURGERY. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1907
During the past few months, in a comparatively small radius, I have known of five deaths directly attributable to general anesthesia. In two instances chloroform was the anesthetizing agent, in two ether and in one somnoform. These represent a relatively small number of cases.
openaire   +2 more sources

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