Effects of Adding Local Anesthesia to General Anesthesia on Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: A Retrospective Cohort Study. [PDF]
Zhong L, Wang R, Huang L.
europepmc +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Gamma knife radiosurgery in pediatric neuro-oncology: histology-specific outcomes and age-adapted procedural strategies. [PDF]
Lee JS, Lee JI, Shin HJ, Choi JW.
europepmc +1 more source
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source
WALANT Thumb CMC Joint Denervation Under Field Sterility: A Case Report and Description of Technique. [PDF]
Platt A, Graff MF, Ponich B, Knox A.
europepmc +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Comparing Complication Rates in Procedures Performed in the Operating Room Versus In-Office: A Cohort Study. [PDF]
Carter JT +5 more
europepmc +1 more source
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
Analgesic and Sedative Effects of Virtual Reality on Children with Acute Pulpitis: A Study Protocol for a Randomised Controlled Trial. [PDF]
Cao W +8 more
europepmc +1 more source
Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee +4 more
wiley +1 more source

