Results 1 to 10 of about 248,446 (274)
MENDELSEEK: An algorithm that predicts mendelian genes and elucidates what makes them special. [PDF]
PLoS Computational BiologyAlthough individual Mendelian diseases-those caused by a single gene-are rare, their collective disease burden is substantial. Identifying the causal gene for each condition is essential for accurate diagnosis and effective treatment.
Hongyi Zhou +2 more
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Rheumatoid arthritis and risk of lung diseases in East Asians and Europeans: Evidence from a Mendelian randomization study [PDF]
SAGE Open MedicineBackground: Rheumatoid arthritis might increase the risk of lung diseases, such as interstitial lung disease and lung cancer. However, the causal relationships remained unclear.
Shengkai Zhang +5 more
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Frontiers in Genetics, 2022 Purpose: Observational research has indicated the presence of a causal relationship between sleep disturbances and low back pain (LBP). However, the link may have been biased by confounding factors.
Peng Shu +4 more
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Journal of Organization Design, 2023 AbstractIn his most recent book, Daniel Levinthal develops a theory of strategy and organization centred around a “Mendelian executive” who consciously seeks new strategic opportunities but is constrained by path dependence to search in spaces adjacent to the current state of affairs.
Marengo, L, Settepanella, S, Valente, M
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Is it possible to implement a rare disease case-finding tool in primary care? A UK-based pilot study
Orphanet Journal of Rare Diseases, 2022 Introduction This study implemented MendelScan, a primary care rare disease case-finding tool, into a UK National Health Service population. Rare disease diagnosis is challenging due to disease complexity and low physician awareness.
Orlando Buendia +9 more
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Genetic and karyotype divergence between parents affect clonality and sterility in hybrids
eLife, 2023 Asexual reproduction can be triggered by interspecific hybridization, but its emergence is supposedly rare, relying on exceptional combinations of suitable genomes.
Anatolie Marta +11 more
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Mendelian Randomization: Concepts and Scope [PDF]
Cold Spring Harbor Perspectives in Medicine, 2021 Mendelian randomization (MR) is a method of studying the causal effects of modifiable exposures (i.e., potential risk factors) on health, social, and economic outcomes using genetic variants associated with the specific exposures of interest. MR provides a more robust understanding of the influence of these exposures on outcomes because germline ...
Richmond, Rebecca, Davey Smith, George
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Unveiling the Mysteries of Non-Mendelian Heredity in Plant Breeding
Plants, 2023 Mendelian heredity is the cornerstone of plant breeding and has been used to develop new varieties of plants since the 19th century. However, there are several breeding cases, such as cytoplasmic inheritance, methylation, epigenetics, hybrid vigor, and ...
Mohsen Yoosefzadeh Najafabadi +2 more
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Episodic neurologic disorders: syndromes, genes, and mechanisms. [PDF]
, 2013 Many neurologic diseases cause discrete episodic impairment in contrast with progressive deterioration. The symptoms of these episodic disorders exhibit striking variety.
Fu, Ying-Hui +2 more
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Mendelian and Non-Mendelian Quadratic Operators [PDF]
Applied Mathematics & Information Sciences, 2013 In this paper, we attempt to provide mathematical models of Mendelian and Non-Mendelian inheritances of the bisexual population system having Fisher's {\textbf{1:1}} principle. In our model, we always assume that distributions of the same phenotype of female and male populations are equal. We study the evolution of a Mendelian trait.
Ganikhodjaev, Nasir +2 more
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