Unveiling the Mysteries of Non-Mendelian Heredity in Plant Breeding
Plants, 2023 Mendelian heredity is the cornerstone of plant breeding and has been used to develop new varieties of plants since the 19th century. However, there are several breeding cases, such as cytoplasmic inheritance, methylation, epigenetics, hybrid vigor, and ...
Mohsen Yoosefzadeh Najafabadi +2 more
doaj +1 more source
Unraveling the directional link between adiposity and inflammation: a bidirectional mendelian randomization approach [PDF]
, 2010 <b>Context</b>: Associations between adiposity and circulating inflammation markers are assumed to be causal, although the direction of the relationship has not been proven. <b>Objective</b>: The aim of the study was to explore
Jukema, J.W. +19 more
core +1 more source
Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study : application to alcohol and cardiovascular traits [PDF]
, 2014 Background: Mendelian randomization studies have so far restricted attention to linear associations relating the genetic instrument to the exposure, and the exposure to the outcome.
Casas, Juan P. +21 more
core +1 more source
Monogenic Lupus: A Developing Paradigm of Disease
Frontiers in Immunology, 2018 Monogenic lupus is a form of systemic lupus erythematosus (SLE) that occurs in patients with a single gene defect. This rare variant of lupus generally presents with early onset severe disease, especially affecting the kidneys and central nervous system.
Jessie M. Alperin +3 more
doaj +1 more source
Interaction Between Mendelian and Non-Mendelian Genes. Regulation of the Transmission of Non-Mendelian Genes by a Mendelian Gene In Chlamydomonas reinhardtii [PDF]
Proceedings of the National Academy of Sciences, 1974 The non-Mendelian genetic element of a given mating type of Chlamydomonas reinhardtii was first doubly marked by succesive mutageneses and then transferred into a number of offspring cells of the opposite mating type.
O M, Chu-Der, K S, Chiang
openaire +2 more sources
Mendelian and non-Mendelian genetics in model plants
The Plant Cell, 2022 Abstract The “Mendelian Rules” of inheritance are cornerstones of genetics, described in Mendel’s seminal publication from 1866. The experimental results and their interpretation have been discussed in numerous ways. This perspective emphasizes the contribution of Mendel’s preparations prior to his crossing experiments to the discovery ...
openaire +2 more sources
Celer: an Efficient Program for Genotype Elimination [PDF]
Electronic Proceedings in Theoretical Computer Science, 2010 This paper presents an efficient program for checking Mendelian consistency in a pedigree. Since pedigrees may contain incomplete and/or erroneous information, geneticists need to pre-process them before performing linkage analysis.
Nicoletta De Francesco +2 more
doaj +1 more source
Causal analysis between gastro-oesophageal reflux disease and obstructive sleep apnoea
ERJ Open Research, 2023 Background Based on evidence from existing observational research, clarifying the causal relationship between gastro-oesophageal reflux disease (GORD) and obstructive sleep apnoea (OSA) is challenging.
Gui Chen +8 more
doaj +1 more source
Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases [PDF]
, 2011 Scientists have been trying to understand the molecular mechanisms of diseases to design preventive and therapeutic strategies for a long time. For some diseases, it has become evident that it is not enough to obtain a catalogue of the disease-related ...
Furlong, Laura I. +21 more
core +1 more source