Results 181 to 190 of about 5,386,243 (355)

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Lumbar plexus combined with sacral plexus nerve block anesthesia in elderly patients undergoing hip surgery. [PDF]

Eur J Med Res
Cao Z.
europepmc   +1 more source

An Ultra‐Flexible Neural Electrode with Bioelectromechanical Compatibility and Brain Micromotion Detection

Advanced Healthcare Materials, EarlyView.
Neural electrodes face a mechanical mismatch with brain tissue. This study proposes a bioelectromechanical coupling strategy using an ultra‐flexible electrode designed for synchronized motion. Optimized to match brain tissue stiffness, it achieves dual signal acquisition and micromotion sensing, with characterized interfacial forces and piezoresistive ...
Donglei Chen, Yu Lu, Shuo Zhang, Wenqi Zhang, Zejie Yu, Shuideng Wang, Zhi Qu, Mingxing Cheng, Yiqing Yao, Deheng Wang, Zhan Yang, Lixin Dong   +11 more
wiley   +1 more source

Efficacy of an Electronic Constant-Speed Injector in Reducing Pain of Local Anesthesia in a Scalp Procedure. [PDF]

Plast Reconstr Surg Glob Open
Hwang ST, Choi EJ, Moon IJ, Kim YJ, Won CH.   +4 more
europepmc   +1 more source

Transient Neurologic Deficit After Spinal Anesthesia: Local Anesthetic Maldistribution with Pencil Point Needles?

Anesthesia and Analgesia, 1995
D. Beardsley, S. Holman, R. Gantt, Ronald A. Robinson, J. Lindsey, M. Bazaral, Sandy F. C. Stewart, R. Stevens   +7 more
semanticscholar   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Perceptions and practices of epinephrine use with local anesthetics in end-arterial areas among Jordanian physicians: A cross-sectional survey. [PDF]

Medicine (Baltimore)
Amarin M, Elayan A, Bani-Khaled F, Shdaifat L, Odeh M, Ismail O, Al Aruri DO, Al-Taher R.   +7 more
europepmc   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Integration of mobile CT and basal anesthesia for pain-free preoperative localization of small pulmonary nodules: a retrospective cohort study. [PDF]

BMC Surg
Yao M, Sun Y, Zhang Q, Shao F.
europepmc   +1 more source