Results 181 to 190 of about 271,269 (260)

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Prospective Multicenter Propensity Score-matched Comparison of Ultrasound-guided Versus Endoscopic Carpal Tunnel Release. [PDF]

J Hand Surg Glob Online
Marwin VM, Nelson JT, Watt JF, Verheyden JR, Perry PE, Warhold LG, Carl DJ, Palmer MJ, Niedermeier SR, Miller LE, Godfrey JM.   +10 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Awake burr hole craniotomy for chronic subdural hematoma: a phase 2 randomized controlled trial. [PDF]

Crit Care
Mertens R, Weber CF, Depperich L, Spindler P, Jelgersma C, Ferdowssian K, Früh A, Truckenmüller P, Almahozi A, Sprünken ED, Keller T, Müller A, Lütz A, Spies C, Töpper F, Treskatsch S, Hecht N, Vajkoczy P, Wessels L.   +18 more
europepmc   +1 more source

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

Comparison of five anesthetic delivery systems for palatal infiltration: A randomized clinical trial. [PDF]

Med Oral Patol Oral Cir Bucal
Küçükkurt S, Saadat A.
europepmc   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

The correlation between preoperative anxiety and postoperative pain in patients undergoing laparoscopic cholecystectomy

Asian Journal of Surgery
Peiwen Gao, Yujun Zhang, Chaoyi Deng, Wensheng Zhang   +3 more
doaj   +1 more source

Number of dermatomes blocked by conventional dose single shot spinal anesthesia for cesarean section is not positively related to hyperbaric bupivacaine dose - a retrospective analysis of 362 cases. [PDF]

BMC Anesthesiol
Horosz B, Morisson W, Białowolska-Horosz K, Malec-Milewska M.   +3 more
europepmc   +1 more source