Results 41 to 50 of about 439,633 (303)

Genetically supported causality between gut microbiota, gut metabolites and low back pain: a two-sample Mendelian randomization study

Frontiers in Microbiology, 2023
BackgroundPrevious studies have implicated a vital association between gut microbiota/gut microbial metabolites and low back pain (LBP), but their causal relationship is still unclear.
Mengchan Su, Mengchan Su, Yidan Tang, Yidan Tang, Weishuang Kong, Shuangyi Zhang, Shuangyi Zhang, Tao Zhu, Tao Zhu   +8 more
doaj   +1 more source

Fast glycorrhachia and cerebrospinal fluid protein as predictors of sensory block in anesthesia with subarachnoid Ropivacaine [PDF]

, 2016
BACKGROUND: Identify if glycorrhachia and cerebrospinal fluid protein could influence the time of sensory block to T10, the duration and the metameric block's level, after a standard dose of Ropivacaine. METHODS: 80 patients, ASA I - III undergoing to
COLLINI, Saul, DE SIO, SIMONE, MERLIN, PAMELA, PACELLA, Elena, PACELLA, FERNANDA, Troisi, F   +5 more
core   +1 more source

Multisite chronic pain and the risk of autoimmune diseases: A Mendelian randomization study

Frontiers in Immunology, 2023
BackgroundAccumulating evidence has demonstrated that an association between chronic pain and autoimmune diseases (AIDs). Nevertheless, it is unclear whether these associations refer to a causal relationship. We used a two-sample Mendelian randomization (
Yidan Tang, Yidan Tang, Weizhi Liu, Weizhi Liu, Weishuang Kong, Shuangyi Zhang, Shuangyi Zhang, Tao Zhu, Tao Zhu   +8 more
doaj   +1 more source

Interpleural analgesia with Morphine and Bupivacaine in pneumothorax

Universidad Médica Pinareña, 2019
Introduction:interpleural block offers postoperative analgesia with significant results in surgical interventions. Objective:to evaluate the benefits of interpleural block with 0.5 % Bupivacaine and Morphine by means of interpleural catheter in patients
Marcos Osuna Ramos, Alejandro Muñoz García, Adrián Alejandro Vitón-Castillo, Celia Fundora-González, Ana Lourdes Martínez Zamora   +4 more
doaj   +2 more sources

Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs

Frontiers in Pharmacology, 2022
Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng, Chaoyi Deng, Jin Liu, Jin Liu, Wensheng Zhang, Wensheng Zhang   +5 more
doaj   +1 more source

Resistance to local anesthesia in people with the Ehlers-Danlos Syndromes presenting for dental surgery

Journal of dental anesthesia and pain medicine, 2019
Background People with the Ehlers-Danlos Syndromes (EDS), a group of heritable disorders of connective tissue, often report experiencing dental procedure pain despite local anesthetic (LA) use.
J. Schubart, E. Schaefer, P. Janicki, S. Adhikary, Amber L. Schilling, A. Hakim, R. Bascom, C. Francomano, S. Raj   +8 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Electroencephalographic depression after abruptly increasing partial pressure of end-tidal carbon dioxide: a case series

BMC Anesthesiology
Background Prolonged electroencephalographic depression during surgery is associated with poor outcomes for patients. However, the published literature on electroencephalographic depression caused by a sudden increase in the partial pressure of end-tidal
Shikuo Li, Yuyi Zhao, Qifeng Wang, Xuehan Li, Chao Chen, Yunxia Zuo   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Enhanced Antitumor Activity of Lidocaine Nanoparticles Encapsulated by a Self-Assembling Peptide

Frontiers in Pharmacology, 2022
Although local anesthetics (LAs) such as lidocaine have been traditionally used for pain relief, their antitumor activity has attracted more and more attentions in recent years.
Yang Yang, Yang Yang, Jiaxiao Sun, Fei Peng, Fei Peng, Haibei Liu, Haibei Liu, Guoyan Zhao, Guoyan Zhao, Junjie Chen, Wensheng Zhang, Wensheng Zhang, Feng Qiu, Feng Qiu   +13 more
doaj   +1 more source