Results 51 to 60 of about 298,237 (314)

Liposome-encapsulated ropivacaine for topical anesthesia of human oral mucosa [PDF]

, 2015
CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOThe elimination of pain caused by needle insertion for local anesthesia would be a significant advance in dentistry.
Bergamaschi, C. D., de Paula, E., Groppo, F. C., Franz-Montan, M., Cogo, K., Volpato, M. C., Ranali, J., Silva, A. L. R.   +7 more
core   +1 more source

Enhanced Antitumor Activity of Lidocaine Nanoparticles Encapsulated by a Self-Assembling Peptide

Frontiers in Pharmacology, 2022
Although local anesthetics (LAs) such as lidocaine have been traditionally used for pain relief, their antitumor activity has attracted more and more attentions in recent years.
Yang Yang, Yang Yang, Jiaxiao Sun, Fei Peng, Fei Peng, Haibei Liu, Haibei Liu, Guoyan Zhao, Guoyan Zhao, Junjie Chen, Wensheng Zhang, Wensheng Zhang, Feng Qiu, Feng Qiu   +13 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Local Anesthesia Systemic Toxicity [PDF]

, 2017
Regional anesthesia can deliver multiple benefits to patients undergoing surgery. However, administering even appropriate doses of local anesthetic agents for regional anesthesia can be life threatening, and the risks must be well understood.
Joel Barton, Gavin Martin
core   +1 more source

Rapid quantification and validation of etomidate and dexmedetomidine blood concentrations in rats using a novel portable mass spectrometer

Frontiers in Veterinary Science
In clinical anesthesia, precise dosing depends on feedback from blood drug concentrations. However, rapid tools for measuring these concentrations are currently limited.
Sicheng Liu, Sicheng Liu, Xiaoxiao Li, Xiaoxiao Li, Deying Gong, Yanhua Huang, Wensheng Zhang, Wensheng Zhang   +7 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Effects of bolus injection rate on the pharmacodynamics and pharmacokinetics of propofol, etomidate and sufentanil in rats

Frontiers in Veterinary Science
IntroductionThe preclinical phase of innovative drug research and development involves a comprehensive assessment of multiple variables that may influence therapeutic outcomes and safety profiles.
Sicheng Liu, Sicheng Liu, Deying Gong, Xiaoxiao Li, Xiaoxiao Li, Feng Qiu, Feng Qiu, Wensheng Zhang, Wensheng Zhang   +8 more
doaj   +1 more source

Efeitos do uso da adrenalina na anestesia local odontológica em portador de coronariopatia Effects of epinephrine in local dental anesthesia in patients with coronary artery disease

Arquivos Brasileiros de Cardiologia, 2007
FUNDAMENTO: A literatura é controversa no que se refere ao uso de vasoconstritores para anestesia local em cardiopatas, havendo preocupação com a indução de descompensação cardíaca.
Ricardo Simões Neves, Itamara Lucia Itagiba Neves, Dante Marcelo Artigas Giorgi, Cesar José Grupi, Luís Antonio Machado César, Whady Hueb, Max Grinberg   +6 more
doaj   +1 more source

Diplopia with local anesthesia

National Journal of Maxillofacial Surgery, 2011
A variety of local and systemic complications can occur during the administration of local anesthesia (LA). Diplopia is one of the very rare complications that follow a posterior superior alveolar (PSA) nerve block. This article describes a very rare case report and the possible mechanisms are discussed in detail.
Pragasm, Michael, Managutti, Anil
openaire   +3 more sources

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source