Results 41 to 50 of about 6,534,475 (234)
Frontiers in Microbiology, 2023 BackgroundPrevious studies have implicated a vital association between gut microbiota/gut microbial metabolites and low back pain (LBP), but their causal relationship is still unclear.
Mengchan Su +8 more
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Propofol Anesthesia Impairs the Maturation and Survival of Adult-born Hippocampal Neurons [PDF]
, 2013 BACKGROUND:: Adult neurogenesis occurs in the hippocampus of most mammals, including humans, and plays an important role in hippocampal-dependent learning. This process is highly regulated by neuronal activity and might therefore be vulnerable to
Krzisch, M. +17 more
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Interpleural analgesia with Morphine and Bupivacaine in pneumothorax
Universidad Médica Pinareña, 2019 Introduction:interpleural block offers postoperative analgesia with significant results in surgical interventions. Objective:to evaluate the benefits of interpleural block with 0.5 % Bupivacaine and Morphine by means of interpleural catheter in patients
Marcos Osuna Ramos +4 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
BMC AnesthesiologyBackground Prolonged electroencephalographic depression during surgery is associated with poor outcomes for patients. However, the published literature on electroencephalographic depression caused by a sudden increase in the partial pressure of end-tidal
Shikuo Li +5 more
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Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs
Frontiers in Pharmacology, 2022 Among the advancements in drug structural modifications, the increased focus on drug metabolic and pharmacokinetic properties in the anesthetic drug design process has led to significant developments.
Chaoyi Deng +5 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Department of Anesthesia. University of Iowa. Spring 2009. [PDF]
, 2009 University of Iowa Department of Anesthesia ...
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Archives of Plastic Surgery, 2016 Background One-per-mil tumescent solution, which contains 0.2% lidocaine with 1:1,000,000 epinephrine, has been reported to be clinically effective for hand surgery under local anesthesia. However, it was lacking in its basic pharmacokinetics profile in
Theddeus O.H. Prasetyono +1 more
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