Results 91 to 100 of about 139,216 (254)

Comparison of Recovery Period, Gastrointestinal and Respiratory Side Effects in Spinal Anesthesia with Hyperbaric Marcaine in Diabetic and Non-diabetic Patients

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2013
Introduction: Spinal anesthesia via Marcaine hyperbaric in different patients is associated with different side effects. The present study was performed to detect recovery period, Gastrointestinal and Respiratory side effects in spinal anesthesia with ...
F Yadollahi, A Khaledifar, A Sheraft, Sh Shalehi   +3 more
doaj  

The changes in Bispectral index during recovery period in tracheal intubation general Anesthesia with or without tracheal-laryngopharynx topical Anesthesia

Asian Journal of Surgery, 2022
Run-qiao Fu, Mian-rong Xue, Li-hong Wang, Wang-yan Yang   +3 more
openaire   +3 more sources

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Total intravenous anesthesia: propofol/remifentanil vs midazolam/remifentanil in thoracic surgery

Revista Cubana de Anestesiología y Reanimación, 2020
Introduction:Anesthesia administration techniques in thoracic surgery have undergone great evolution and greater scientific foundation. Total intravenous anesthesia based on analgesia favors the perioperative period without pain and recovery without ...
Miriam Falcón Guerra, Sergio A Orizondo Pajón, Jorge A Alonso Valdés, Isis Nicolau Cruz   +3 more
doaj   +2 more sources

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

The related factors and countermeasures of hypothermia in patients during the anesthesia recovery period.

American journal of translational research
This research aims to explore and analyze the risk factors that lead to hypothermia in patients in the post-anesthesia care unit (PACU) and to investigate the heat preservation effects of the various heat preservation measures.A total of 224 patients who entered the PACU from February 2018 to October 2018 after anesthesia surgery in our hospital were ...
Mei, Liu, Lei, Qi
openaire   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Influence of general anesthesia and surgical procedure on functional recovery following rat sciatic nerve transection and repair

Ukrainian Neurosurgical Journal
Objective. To evaluate the effects of the type of general anesthesia and surgical procedure on sensory and motor functional recovery following sciatic nerve transection with immediate neurorrhaphy in rats. Materials and methods.
Oleksandr V. Bomikhov, Valentyn V. Yarynka, Taras I. Petriv, Ziia K. Melikov, Nana V. Voitenko, Volodymyr V. Medvediev, Pavel V. Belan   +6 more
doaj   +1 more source