Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
Investigate the complications of general anaesthesia with mask in patients under surgery
This research project is a field study to investigate the complications of general anaesthesia with mask in patients under surgery in a hospital affiliated to University of Medical Sciences Iran.
Mehdi poor H
doaj
Bispectral index in calves anesthetized with xylazine, midazolam, ketamine, isoflurane and subjected to continuous rate infusion of lidocaine [PDF]
PURPOSE:To assess the bispectral index (BIS) and recovery in calves anesthetized with xylazine, midazolam, ketamine and isoflurane and subjected to CRI of lidocaine.METHODS:Xilazine was administered followed by ketamine and midazolam, orotracheal ...
Marcelo Augusto de Araújo +6 more
doaj +1 more source
Do Complexity Measures of Frontal EEG Distinguish Loss of Consciousness in Geriatric Patients Under Anesthesia? [PDF]
While geriatric patients have a high likelihood of requiring anesthesia, they carry an increased risk for adverse cognitive outcomes from its use. Previous work suggests this could be mitigated by better intraoperative monitoring using indexes defined by
Caitlin M. Drover +8 more
core +2 more sources
Associations of Sleep and Shift Work With Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source
Retrospective analysis of common complications in neurosurgical postanesthesia care unit
Objective To explore the complications neurosurgical patients with general anesthesia in neurosurgical postanesthesia care unit (PACU), and analyse the probable cause to enhance the safety of neurosurgical patients in perioperative period.
Xue⁃bin LI +5 more
doaj
Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J. +2 more
core +1 more source
Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek +196 more
core +1 more source
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian +4 more
wiley +1 more source
Fatal cardiac tamponade that developed in the post-anesthesia care unit: a rare complication after lung lobectomy [PDF]
Background and objectives: Cardiac tamponade is potentially fatal medical condition, which rarely occurs as a complication of lung lobectomy. We present the first case of cardiac tamponade to develop in a Post-Anesthesia Care Unit following a lung ...
Hyung Mook Lee +4 more
doaj +3 more sources

