Results 61 to 70 of about 4,350,697 (248)

Local anesthetics and their adjuncts [PDF]

open access: yesPediatric Anesthesia, 2011
SummaryLocal anesthetics (LA) block propagation of impulses along nerve fibers by inactivation of voltage‐gated sodium channels, which initiate action potentials (1). They act on the cytosolic side of phospholipid membranes. Two main chemical compounds are used, amino esters and amino amides. Amino esters are degraded by pseudocholinesterases in plasma.
openaire   +2 more sources

Lipid Emulsion for Local Anesthetic Systemic Toxicity [PDF]

open access: yes, 2012
The accidental overdose of local anesthetics may prove fatal. The commonly used amide local anesthetics have varying adverse effects on the myocardium, and beyond a certain dose all are capable of causing death.
Sarah Ciechanowicz, Vinod Patil
core   +1 more source

Palatal ulceration: A local anesthetic complication

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2017
The hard palate is one of the common sites of local complications following administration of local anesthetics. The hard, unyielding palatal tissues coupled with either forceful or excessive administration of solution, induction of trauma, use of ...
Urvashi Sharma
doaj   +1 more source

Is Cardiolipin the Target of Local Anesthetic Cardiotoxicity?

open access: yes, 2010
SummaryBackground and objectivesLocal anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. Local anesthetic-induced cardiotoxic reaction has been considered the accidental event without currently effective ...
Yuan, HongMei   +10 more
core   +1 more source

Local Anesthetics

open access: yesPain, 2018
Cocaine is a naturally occurring compound indigenous to the Andes Mountains, West Indies, and Java. It was the first anesthetic to be discovered and is the only naturally occurring local anesthetic; all others are synthetically derived.
Carol L. Schroeder   +1 more
semanticscholar   +1 more source

Impact of hyaluronidase on anesthetic distribution in retrobulbar region following sub-Tenon anesthesia [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Sub-Tenon's block is nowadays commonly used in ophthalmic surgery because of its safety and efficacy. The aim of this study was to investigate the distribution of the anesthetic solution with different amounts of hyaluronidase in the ...
Šurbatović Maja   +5 more
doaj   +1 more source

β–Cyclodextrin–Propyl Sulfonic Acid Catalysed One-Pot Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles as Local Anesthetic Agents

open access: yesMolecules, 2015
Some functionalized 1,2,4,5-tetrasubstituted imidazole derivatives were synthesized using a one-pot, four component reaction involving 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines.
Yan Ran, Ming Li, Zong-Ze Zhang
doaj   +1 more source

Local anesthetic "lidocaine hydrochloride" generates oxygen radicals under coexistence with xanthine oxidase

open access: yes, 2002
P(論文)This study investigated whether or not lidocaine, one of the most widely used local anesthetics in dentistry, reacts with xanthine oxidase and generates superoxide radicals (O_2^) and/or some other oxygen radicals.
佐藤, 尚武, 26479
core  

Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence

open access: yesJournal of Translational Medicine, 2018
The relationship between surgery and anesthetic-induced immunosuppression and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system (SNS) to cause ...
R. Kim
semanticscholar   +1 more source

Local Anesthetic “Resistance”

open access: yesPain Physician, 2003
The incidence of inadequate analgesia despite technically well performed injections led our clinic to prospectively test patients for response to a variety of local aesthetics. Skin testing was performed on the skin of the forearm away from the site of pathology. Patients were asked to identify "which is the most numb" of the skin wheals. Although most
openaire   +2 more sources

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