Results 71 to 80 of about 470,729 (391)

Local anesthetic toxicity: acute and chronic management

Acute Medicine & Surgery, 2017
Local anesthetics are commonly used medicines in clinical settings. They are used for pain management during minor interventional treatments, and for postoperative care after major surgeries. Cocaine is the well‐known origin of local anesthetics, and the
Kenichi Sekimoto, M. Tobe, S. Saito
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

THE AMOUNT OF THE ANESTHETIC. [PDF]

JAMA: The Journal of the American Medical Association, 1900
The anesthetic is undoubtedly a prominent etiologic factor in the disturbances which accompany and follow surgcal operations. To it may be attributed, directly or indirectly, much of the rapid pulse and respiration, exhaustion, shock, nausea, vomiting, asphyxia, syncope, bronchitis, pneumonia, pulmonary edema, and nephritis seen in connection with ...
openaire   +3 more sources

SENSORY REGRESSION TIME FROM SUBARACHNOID BLOCK WITH HYPERBARIC 0.75% BUPIVACAINE IN THE OBESE PATIENT [PDF]

, 1989
The purpose of this study was to determine if obese patients have a different sensory regression time from subarachnoid block than non-obese patients using hyperbaric 0.75% bupivacaine. A quasi-experimental design was used. Twenty patients were separated
Hilton, George Leslie
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Pheochromocytoma resection: Current concepts in anesthetic management

Journal of Anaesthesiology Clinical Pharmacology, 2015
Pheochromocytoma represents very significant challenges to the anesthetist, especially when undiagnosed. These chromaffin tissue tumors are not uncommon in anesthetic practice and have varied manifestations.
H. Ramakrishna
semanticscholar   +1 more source

Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]

, 2015
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul, PACELLA, Elena, PACELLA, FERNANDA, SALDUCCI, Mauro, SMALDONE, GIANPAOLO, Troisi, Fabiana, TURCHETTI, PAOLO   +6 more
core   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

NOTES ON ANESTHETICS. [PDF]

JAMA: The Journal of the American Medical Association, 1901
A man can not do two things at once so skilfully as he can do either one of them by itself. A surgeon can not do his most skilful operating while devoting half his attention to the anesthetic. A surgeon is frequently more concerned about the result of the anesthetizer's work than he is about the results of his own work.
openaire   +3 more sources

Comparison of the Anesthetic Techniques [PDF]

The Scientific World Journal, 2015
A great number of anesthetic techniques (general, regional, spinal, epidural, caudal, hypotensive, total intravenous, regional intravenous, inhalation, and nerve blocks) can be used for multiple surgical procedures [1–3]. The effect of anesthetic technique on perioperative outcomes is controversial.
Ahmet Eroglu, Alparslan Apan, Engin Erturk, Izhar Ben-Shlomo   +3 more
openaire   +5 more sources