Results 151 to 160 of about 1,731 (219)

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

Intravenous Ketamine to Facilitate Transport of Agitated Patients to the ECT Clinic. [PDF]

J ECT
Dean O, Byford-Brooks A, Hannigan K, Saunders D, Gamble W, Kirov G.   +5 more
europepmc   +1 more source

Real‐Time In Vivo Visualization of Tumor‐Associated Macrophage Reprogramming Using a Nitric Oxide‐Activatable NIR‐II Nanoinducer

Advanced Science, EarlyView.
Reprogramming tumor‐associated macrophages is a promising therapeutic strategy for solid tumors. Here, a nitric oxide (NO)‐activatable NIR‐II fluorescence/photoacoustic nanoinducer (I/E@M2pep) that simultaneously facilitates and visualizes the repolarization of TAMs to an M1‐like phenotype is reported, thereby enhancing anti‐tumor efficacy through M1 ...
Qian Chen, Meng Li, Tuanwei Li, Chen Yang, Xiaohu Yang, Hongchao Yang, Yejun Zhang, Chunyan Li, Qiangbin Wang   +8 more
wiley   +1 more source

Near-Death Experience During Emergency Ketamine Use: A Case Report. [PDF]

Brain Behav
Fritz P, Pichelin A, Ancion A, Alnagger N, Lejeune N, Ghuysen A, Gosseries O, Martial C.   +7 more
europepmc   +1 more source

A Conformal Wearable Ultrasound Bioelectronics for Mechanotherapy Reprogramming of Fibroblast Plasticity via Wnt‐FGF10 Axis to Overcome Fibrotic Healing in Urethral Regeneration

Advanced Science, EarlyView.
Fibrotic scarring persistently challenges urethral reconstruction. This study introduces a conformal, wearable ultrasound bioelectronic system that overcomes this by reprogramming fibroblast fate. The device activates a developmental Wnt–FGF10 axis, driving fibroblasts toward a regenerative FGF10+ phenotype that promotes angiogenesis and matrix ...
Mingming Yu, Xingxuan Zhang, Huan Zhang, Jun Wang, Fang Chen, Xiaojun Cai, Yichen Huang, Yuanyi Zheng   +7 more
wiley   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Interactions Between Anesthesia and Sleep: Optimizing Perioperative Care to Improve Sleep Quality and Surgical Recovery Outcomes. [PDF]

Cureus
Patel S, Ownby R.
europepmc   +1 more source

Isovolumic relaxation strain imaging is an accurate and sensitive approach for detection of active diastolic dysfunction: A preclinical study

Animal Models and Experimental Medicine, EarlyView.
A modified approach was developed to accurately identify the isovolumetric relaxation time (IVRT) using an apical three‐chamber view. Compared with conventional echocardiography, isovolumic relaxation strain imaging (IVSI) helps to detect the earlier alternations of diastolic function in transverse aortic constriction (TAC) mice.
Jingjing Liang, Juncheng Wang, Jun Cheng, Yanggan Wang   +3 more
wiley   +1 more source

Gas necrosis and sepsis due to recreational ketamine use. [PDF]

Rev Inst Med Trop Sao Paulo
Bezerra AS, Vazquez CMP, Guilherme ACT, Rodrigues ABR, Crivillari MB, Queiroz W.   +5 more
europepmc   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source