Results 21 to 30 of about 6,404,771 (353)

General Anesthetics Activate a Potent Central Pain-Suppression Circuit in the Amygdala

Nature Neuroscience, 2020
General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA suppresses pain in part by activating supraspinal analgesic circuits.
Thuy Hua, Bin Chen, Dongye Lu, Katsuyasu Sakurai, Shengli Zhao, Bao-xia Han, Jiwoo Kim, Luping Yin, Yong Chen, Jinghao Lu, Fan Wang   +10 more
semanticscholar   +1 more source

The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]

Korean Journal of Anesthesiology, 2014
BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee, Yong-Hee Park, Hyun-Gul Song, Hee-Pyoung Park, Hee-Soo Kim, Chong-Sung Kim, Jin-Tae Kim   +6 more
doaj   +1 more source

General Anesthetics on Immune System Cytokines: A Narrative Review Article

Anesthesiology and Pain Medicine, 2020
Context According to the previous studies, general anesthesia influences the immune system. Evaluating such impacts on the immune system helps to improve the management of anesthesia.
A. Jafarzadeh, M. Hadavi, G. Hassanshahi, M. Rezaeian, R. Vazirinejad   +4 more
semanticscholar   +1 more source

Volatile anesthetics maintain tidal volume and minute ventilation to a greater degree than propofol under spontaneous respiration

BMC Anesthesiology, 2021
Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao, Mengchan Ou, Yu Li, Cheng Zhou   +3 more
doaj   +1 more source

Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling

Frontiers in Oncology, 2021
Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators.
Jiaqiang Wang, Chien-shan Cheng, Chien-shan Cheng, Yan Lu, Shen Sun, Shaoqiang Huang   +5 more
doaj   +1 more source

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR, Brosnan, RJ, Fletcher, DJ, Holliday, TA, Kass, PH, LeCouteur, RA, Steffey, EP, Tharp, B, Williams, DC   +8 more
core   +1 more source

Anesthetic management of a 9-year-old girl with Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay syndrome: airway difficulties and postoperative apnea during tendon surgery [PDF]

Anesthesia and Pain Medicine
Background This case report described the anesthetic management and postoperative challenges of a patient diagnosed with Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay (CLIFAHDD) syndrome who underwent tenomyotomy of ...
Jessica G. Santos, Alexandre C. Buffon
doaj   +1 more source

Research progress on molecular mechanisms of general anesthetic-induced neurotoxicity and cognitive impairment in the developing brain

Frontiers in Neurology, 2022
General anesthetics-induced neurotoxicity and cognitive impairment in developing brains have become one of the current research hotspots in the medical science community.
Jiaojiao Wang, Jiaojiao Wang, Zhihui Liu
doaj   +1 more source

Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review

Frontiers in Synaptic Neuroscience, 2022
General anesthetics disrupt brain processes involved in consciousness by altering synaptic patterns of excitation and inhibition. In the cerebral cortex and hippocampus, GABAergic inhibition is largely mediated by inhibitory interneurons, a heterogeneous
Iris A. Speigel, Hugh C. Hemmings Jr., Hugh C. Hemmings Jr.   +2 more
doaj   +1 more source