Results 31 to 40 of about 952,770 (304)
Frontiers in Synaptic Neuroscience, 2022 General anesthetics disrupt brain processes involved in consciousness by altering synaptic patterns of excitation and inhibition. In the cerebral cortex and hippocampus, GABAergic inhibition is largely mediated by inhibitory interneurons, a heterogeneous
Iris A. Speigel +2 more
doaj +1 more source
A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain
Brain Sciences, 2014 The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj +1 more source
The use of anesthetics for cesarean section delivery in women in Duhok, Kurdistan region, Iraq
Journal of Ideas in Health, 2022 Background: Limited information is available on anesthetics that are preferred or used by anesthesiologists for cesarean section (CS) delivery in Kurdistan region, Iraq.
Rozheen Shukry Karam +1 more
doaj +1 more source
Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]
, 2018 Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W. +4 more
core +2 more sources
Common anesthetic molecules prefer to partition in liquid disorder phase domain in a composite multicomponent membrane [PDF]
Phys. Rev. E 98, 012409 (2018), 2018 Despite a vast clinical application of anesthetics, the molecular level of understanding of general anesthesia is far from our reach. Using atomistic molecular dynamics simulation, we study the effects of common anesthetics: ethanol, chloroform and methanol in the fully hydrated symmetric multicomponent lipid bilayer membrane comprising of an ...
arxiv +1 more source
BMC Anesthesiology, 2018 Background This study aimed to determine whether the use of desflurane (DES) anesthesia combined with bispectral index (BIS) monitoring and warming is effective in reducing anesthesia-controlled operating room time (ACT) in patients undergoing lengthy ...
Hong Yu, Lu Zhang, Ye Ma, Hai Yu
doaj +1 more source
Membrane Nanodomains Homeostasis During Propofol Anesthesia as Function of Dosage and Temperature [PDF]
, 2020 Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, often encountered complications such as anesthesia induced amnesia are not understood. General anesthetics are hydrophobic molecules easily dissolving into lipid bilayers.
arxiv +1 more source
Radical pairs may play a role in xenon-induced general anesthesia [PDF]
Sci Rep 11, 6287 (2021), 2020 Understanding the mechanisms underlying general anesthesia would be a key step towards understanding consciousness. The process of xenon-induced general anesthesia has been shown to involve electron transfer, and the potency of xenon as a general anesthetic exhibits isotopic dependence. We propose that these observations can be explained by a mechanism
arxiv +1 more source
Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
, 2014 BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources
The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]
, 2012 This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L +5 more
core +1 more source