Results 31 to 40 of about 6,408,160 (262)

Early postoperative recovery in operating room after desflurane anesthesia combined with Bispectral index (BIS) monitoring and warming in lengthy abdominal surgery: a randomized controlled study

BMC Anesthesiology, 2018
Background This study aimed to determine whether the use of desflurane (DES) anesthesia combined with bispectral index (BIS) monitoring and warming is effective in reducing anesthesia-controlled operating room time (ACT) in patients undergoing lengthy ...
Hong Yu, Lu Zhang, Ye Ma, Hai Yu
doaj   +1 more source

A mini-review of the effects of inhalational and intravenous anesthetics on oxidative stress in dogs

Frontiers in Veterinary Science, 2022
General anesthesia increases the production of reactive oxygen species (ROS), which can exacerbate or increase oxidative stress and thus affect the prognosis of surgical procedures.
Katerina Tomsič, Alenka Nemec Svete
doaj   +1 more source

Inhaled Anesthetics: Environmental Role, Occupational Risk, and Clinical Use

Journal of Clinical Medicine, 2021
Inhaled anesthetics have been in clinical use for over 150 years and are still commonly used in daily practice. The initial view of inhaled anesthetics as indispensable for general anesthesia has evolved during the years and, currently, its general use ...
Mariana Gaya da Costa, A. Kalmar, M. Struys   +2 more
semanticscholar   +1 more source

Regulatory Effect of General Anesthetics on Activity of Potassium Channels

Neuroscience Bulletin, 2018
General anesthesia is an unconscious state induced by anesthetics for surgery. The molecular targets and cellular mechanisms of general anesthetics in the mammalian nervous system have been investigated during past decades.
Yan Li, Jie Xu, Yun Xu, Xiao-Yun Zhao, Ye Liu, Jie Wang, Guang-Ming Wang, Yan-Tian Lv, Qiong-Yao Tang, Zhe Zhang   +9 more
semanticscholar   +1 more source

Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness

Front. Neural Circuits, 2017
There has been controversy regarding the precise mechanisms of anesthetic-induced unconsciousness, with two salient approaches that have emerged within systems neuroscience.
G. Mashour, A. Hudetz
semanticscholar   +1 more source

Long-term effects of neonatal single or multiple isoflurane exposures on spatial memory in rats

Frontiers in Neurology, 2013
General anesthetics are neurotoxic to neonatal rodents and nonhuman primates. Neonatal exposure to general anesthetics has been associated with long-term cognitive deficits in animal models. Some data from humans are consistent with long-term deleterious
Kathy L Murphy, Mark G Baxter
doaj   +1 more source

General anesthetic action profile on the human prefrontal cortex cells through comprehensive single-cell RNA-seq analysis

iScience, 2023
Summary: The cellular and molecular actions of general anesthetics to induce anesthesia state and also cellular signaling changes for subsequent potential “long term” effects remain largely elusive.
Enqiang Chang, Yangyang Wang, Ruilou Zhu, Lingzhi Wu, Yitian Yang, Shuang Zeng, Ningtao Li, Xiaoguo Ruan, Mingyang Sun, Wei Zhang, Jun Zhou, Mengrong Miao, Hui Zhi, Hailin Zhao, Qian Chen, Qizhe Sun, Emer Chang, Albert Chang, Tingting Zhang, Xinfang He, Kan Liu, Songhua Ma, Weizhong Zhu, Youming Zhang, Luca Magnani, Daqing Ma, Jiaqiang Zhang   +26 more
doaj   +1 more source

Parosmia and dysgeusia after intravenous propofol-based general anesthesia: A case report

Annals of Cardiac Anaesthesia, 2022
Various drugs, including anesthetic agents, can cause parosmia in the perioperative period. There are reported cases of patients with alterations of smell and taste due to local anesthetics, nerve damage, or as a side effect of general anesthesia.
Nayab Farzana, Prabhat Tewari, Sanjoy Sureka, Aanchal Dixit   +3 more
doaj   +1 more source

General Anesthetics: Aspects of Chirality, Pharmacodynamics, and Pharmacokinetics

Pharmaceuticals
The introduction of general anesthetics in the mid-19th century is considered one of the greatest contributions to medical practice. It was the first time that complicated surgical interventions became feasible, without putting an excessive strain on the
Ružena Čižmáriková, Ladislav Habala, Jindra Valentová   +2 more
doaj   +1 more source

Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles

Frontiers in Neurology, 2012
Exposure to general anesthetics and antiepileptics during critical stages of brain development causes significant neurotoxicity to immature neurons.
Vesna eJevtovic-Todorovic, Annalisa eBoscolo, Victoria eSanchez, Nadia eLunardi   +3 more
doaj   +1 more source