Results 41 to 50 of about 952,770 (304)
The Role of Neuroactive Steroids in Analgesia and Anesthesia: An Interesting Comeback?
Published evidence over the past few decades suggests that general anesthetics could be neurotoxins especially when administered at the extremes of age.
Vesna Jevtovic-Todorovic+1 more
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Long-term effects of neonatal single or multiple isoflurane exposures on spatial memory in rats
General anesthetics are neurotoxic to neonatal rodents and nonhuman primates. Neonatal exposure to general anesthetics has been associated with long-term cognitive deficits in animal models. Some data from humans are consistent with long-term deleterious
Kathy L Murphy, Mark G Baxter
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General anesthetics are administered to approximately 50 million patients each year in the United States. Anesthetic vapors and gases are also widely used in dentists’ offices, veterinary clinics, and laboratories for animal research. All the volatile anesthetics that are currently used are halogenated compounds destructive to the ozone layer.
openaire +2 more sources
A mini-review of the effects of inhalational and intravenous anesthetics on oxidative stress in dogs
General anesthesia increases the production of reactive oxygen species (ROS), which can exacerbate or increase oxidative stress and thus affect the prognosis of surgical procedures.
Katerina Tomsič, Alenka Nemec Svete
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Perioperative Neurocognitive Disorder: State of the Preclinical Science. [PDF]
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not intended
Culley, Deborah J+10 more
core
Liquid general anesthetics lower critical temperatures in plasma membrane vesicles [PDF]
A large and diverse array of small hydrophobic molecules induce general anesthesia. Their efficacy as anesthetics has been shown to correlate both with their affinity for a hydrophobic environment and with their potency in inhibiting certain ligand gated ion channels.
arxiv +1 more source
ETHYL CHLORID AS A GENERAL ANESTHETIC. [PDF]
I have lately noticed inThe Journalvarious articles on the use of ethyl chlorid as a short general anesthetic, and some specially constructed masks. To my mind the latter are too expensive for the general practitioner, and I desire to present a method that I use in the receiving ward of the Cincinnati Hospital.
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General Anesthetic Techniques in Swine
General anesthesia techniques for swine can be challenging due to the animal's temperament, anatomic traits, physical condition, and the environment in which the clinician may be working. Taking these factors into consideration, this article provides specific information on preanesthetic considerations, venous catheterization, drug selection ...
Paula F. Moon, Lesley J. Smith
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Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles
Exposure to general anesthetics and antiepileptics during critical stages of brain development causes significant neurotoxicity to immature neurons.
Vesna eJevtovic-Todorovic+3 more
doaj +1 more source
On the action potential as a propagating density pulse and the role of anesthetics [PDF]
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings on nerves that are not contained in this classical theory.
ANDREW D. JACKSON+13 more
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