Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance General anesthetics are essential to modern medicine, yet their molecular mechanisms remain poorly understood. Whether general anesthetics primarily act by altering lipid bilayer properties or by interacting directly with specific membrane ...
K. Herold +4 more
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Long-term effects of neonatal single or multiple isoflurane exposures on spatial memory in rats
Frontiers in Neurology, 2013 General anesthetics are neurotoxic to neonatal rodents and nonhuman primates. Neonatal exposure to general anesthetics has been associated with long-term cognitive deficits in animal models. Some data from humans are consistent with long-term deleterious
Kathy L Murphy, Mark G Baxter
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General Anesthetic Techniques in Swine
Veterinary Clinics of North America: Food Animal Practice, 1996 General anesthesia techniques for swine can be challenging due to the animal's temperament, anatomic traits, physical condition, and the environment in which the clinician may be working. Taking these factors into consideration, this article provides specific information on preanesthetic considerations, venous catheterization, drug selection ...
Paula F. Moon, Lesley J. Smith
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Prevalence of general anesthetics use in the Clinic of Surgery at the University Clinical Center of Kosovo [PDF]
Introduction - Anesthesia is a state of controlled, temporary loss of sensation or consciousness that is induced for various medical purposes. It refers to the use of medications (called anesthetics) so that we do not feel pain during procedures or ...
Hakaj, Jehona
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General Anesthetics: Aspects of Chirality, Pharmacodynamics, and Pharmacokinetics
PharmaceuticalsThe introduction of general anesthetics in the mid-19th century is considered one of the greatest contributions to medical practice. It was the first time that complicated surgical interventions became feasible, without putting an excessive strain on the
Ružena Čižmáriková +2 more
doaj +1 more source
Prevalence Of General Anesthetics In The General Surgery Clinic At The University Clinical Center Of Kosovo [PDF]
Introduction – Anesthesia is a controlled, temporary state of insensitivity or unconsciousness induced for various medical purposes. It involves the use of medications (called anesthetics) to prevent pain during procedures or surgery.Objective – The aim ...
Hoxhaj, Vesa, Mala, Arlind
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Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles
Frontiers in Neurology, 2012 Exposure to general anesthetics and antiepileptics during critical stages of brain development causes significant neurotoxicity to immature neurons.
Vesna eJevtovic-Todorovic +3 more
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Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
, 2014 BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
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Parosmia and dysgeusia after intravenous propofol-based general anesthesia: A case report
Annals of Cardiac Anaesthesia, 2022 Various drugs, including anesthetic agents, can cause parosmia in the perioperative period. There are reported cases of patients with alterations of smell and taste due to local anesthetics, nerve damage, or as a side effect of general anesthesia.
Nayab Farzana +3 more
doaj +1 more source
Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]
, 2018 Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W. +4 more
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