Results 101 to 110 of about 42,688 (314)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Editorial: Impact of anesthetics on cancer behavior and outcome

Frontiers in Pharmacology, 2022
Jui-An Lin, Jui-An Lin, Jui-An Lin, Jui-An Lin, Jui-An Lin, Jui-An Lin, Jui-An Lin, Daqing Ma, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu, Szu-Yuan Wu   +13 more
doaj   +1 more source

Anesthetic Techniques and Cancer Recurrence after Surgery

The Scientific World Journal, 2014
Many of the most common anesthetics are used in surgical oncology, yet effects on cancer cells are still not known. Anesthesia technique could differentially affect cancer recurrence in oncologic patients undergoing surgery, due to immunosuppression ...
Vincenzo Fodale, Maria G. D’Arrigo, Stefania Triolo, Stefania Mondello, Domenico La Torre   +4 more
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Attenuation of intestinal ischemia-reperfusion-injury by anesthetics: a potentially protective effect of anesthetic management in experimental studies

Frontiers in Pharmacology
Intestinal ischemia-reperfusion injury (IRI) is a potentially severe clinical syndrome after major surgical procedures. In addition to causing intestinal mucosa injury, intestinal IRI further damages distant organs, causing the severity of the condition ...
Zhan Huang, Zhan Huang, Zhan Huang, Yiping Bai, Yiping Bai, Ying Chen, Ying Chen, Ye Chen, Ye Chen, Yuan Jiang, Jun Zhou, Jun Zhou   +11 more
doaj   +1 more source

Active Emergence from Propofol General Anesthesia Is Induced by Methylphenidate [PDF]

, 2011
Background: A recent study showed that methylphenidate induces emergence from isoflurane general anesthesia. Isoflurane and propofol are general anesthetics that may have distinct molecular mechanisms of action.
Brown, Emery N., Chemali, Jessica J., Solt, Ken, Van Dort, Christa J.   +3 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Dexmedetomidine Associated with Intraoperative Floppy Iris Syndrome in Ophthalmic Surgery [PDF]

Journal of Clinical and Diagnostic Research, 2020
Inci Dersu
doaj   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Inhaled anesthesia associated with reduced mortality in patients with stage III breast cancer: A population-based study.

PLoS ONE
BackgroundPatients diagnosed with stage III breast cancer often undergo surgery, radiation therapy, and chemotherapy as part of their treatment. The choice of anesthesia technique during surgery has been a subject of interest due to its potential ...
Emily Tzu-Jung Kuo, Chin Kuo, Cheng-Li Lin   +2 more
doaj   +1 more source