Results 1 to 10 of about 17,615 (244)

Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling [PDF]

Frontiers in Oncology, 2021
Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators.
Chien-shan Cheng
exaly   +4 more sources

Sodium Channels as Targets for Volatile Anesthetics [PDF]

Frontiers in Pharmacology, 2012
The molecular mechanisms of modern inhaled anesthetics although widely used in clinical settings are still poorly understood. Considerable evidence supports effects on membrane proteins such as ligand- and voltage-gated ion channels of excitable cells ...
Karl F Herold, Hugh C Hemmings Jr
exaly   +5 more sources

The effects of volatile anesthetics and propofol in patients undergoing off-pump coronary artery bypass grafting: a systematic review and meta-analysis [PDF]

Frontiers in Cardiovascular Medicine, 2023
BackgroundStudies investigating the cardioprotective effect of volatile anesthetics on cardiac troponins in off-pump coronary artery bypass grafting (OPCAB) surgery remain controversial.
Chenghong Zhang, Changlin He, Zhengwei Chen, Xin Chen, Junjun Qin, Yuhui Xu, Jiasen Ma   +6 more
doaj   +2 more sources

Relationship between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage [PDF]

Journal of Anesthesia, Analgesia and Critical Care
Background Volatile anesthetics have been suggested to exert neuroprotective effects in patients with subarachnoid hemorrhage caused by a ruptured cerebral aneurysm. However, their effects on functional outcomes remain unverified.
Yudai Iwasaki, Kunio Tarasawa, Yu Kaiho, Saori Ikumi, Takahiro Imaizumi, Shizuha Yabuki, Kiyohide Fushimi, Kenji Fujimori, Masanori Yamauchi   +8 more
doaj   +2 more sources

Development of NMDA receptors contributes to the enhancement of electroencephalogram oscillations under volatile anesthetics in rats [PDF]

Frontiers in Neural Circuits, 2022
BackgroundVolatile anesthetics including sevoflurane and isoflurane enhance oscillations of cortical electroencephalogram (EEG), partly by their modulations on glutamate-mediated excitatory synaptic transmission. Expression of NMDA receptors is increased
Mingyue Zhang, Mingyue Zhang, Yali Chen, Yali Chen, Jin Liu, Jin Liu, Yaoxin Yang, Yaoxin Yang, Rurong Wang, Donghang Zhang, Donghang Zhang, Tao Zhu   +11 more
doaj   +2 more sources

Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I. [PDF]

PLoS ONE, 2012
Anesthetics are in routine use, yet the mechanisms underlying their function are incompletely understood. Studies in vitro demonstrate that both GABA(A) and NMDA receptors are modulated by anesthetics, but whole animal models have not supported the role ...
Albert Quintana, Philip G Morgan, Shane E Kruse, Richard D Palmiter, Margaret M Sedensky   +4 more
doaj   +8 more sources

Volatile anesthetics in the intensive care unit [PDF]

Anaesthesiology Intensive Therapy
The use of volatile anesthetics as an alternative sedation modality in the intensive care unit (ICU) has gained traction over the last several years.
Alexander Morrison-Nozik, Marcin Wąsowicz   +1 more
doaj   +2 more sources

Prolonged in vitro anti-bacterial, anti-inflammatory, and surfactant-promoting effects of volatile anesthetics [PDF]

BMC Pulmonary Medicine
Background Volatile anesthetics are gaining recognition for their benefits in long-term sedation of mechanically ventilated patients with bacterial pneumonia and acute respiratory distress syndrome.
Claudia Scheffzük, Johanna Lührmann, Robin Brinkmann, Dominika Biedziak, Kristina Gloystein, Patrick Kellner, Cordula Stamme   +6 more
doaj   +2 more sources

Effects of Volatile Anesthetics on Postoperative Ischemic Stroke Incidence [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Preclinical studies suggest that volatile anesthetics decrease infarct volume and improve the outcome of ischemic stroke. This study aims to determine their effect during noncardiac surgery on postoperative ischemic stroke incidence.
Dana Raub, Katharina Platzbecker, Stephanie D. Grabitz, Xinling Xu, Karuna Wongtangman, Stephanie B. Pham, Kadhiresan R. Murugappan, Khalid A. Hanafy, Ala Nozari, Timothy T. Houle, Samir M. Kendale, Matthias Eikermann   +11 more
doaj   +2 more sources

Characteristics and Outcomes of Patients Receiving Volatile Anesthetics in Near-Fatal Asthma: A Retrospective Observational Cohort Study [PDF]

Critical Care Explorations
IMPORTANCE AND OBJECTIVES:. Inhaled volatile anesthetics are employed as rescue therapy in near-fatal asthma, despite limited evidence. This study aims to describe the characteristics, management, and outcomes of mechanically ventilated adult patients ...
Christopher Remmington, MPharm, Luigi Camporota, MD, PhD, Daniel Taylor, MD, Angelo Sousa, BSc, Barnaby Sanderson, MSc, Guy Glover, MD   +5 more
doaj   +2 more sources