Short-term one-lung ventilation does not influence local inflammatory cytokine response after lung resection [PDF]
, 2018 Background: One-lung ventilation (OLV) is a ventilation procedure used for pulmonary resection which may results in lung injury. The aim of this study was to evaluate the local inflammatory cytokine response from the dependent lung after OLV and its ...
Andreetti, Claudio +10 more
core +1 more source
Medicina, 2022 Most patients suffering from neoplastic diseases will at some point during their illness be approached surgically. Surgery itself may be unfortunately responsible for tumor proliferation and metastatic spread.
John Michael Bonvini
doaj +1 more source
Regional knockdown of NDUFS4 implicates a thalamocortical circuit mediating anesthetic sensitivity. [PDF]
PLoS ONE, 2017 Knockout of the mitochondrial complex I protein, NDUFS4, profoundly increases sensitivity of mice to volatile anesthetics. In mice carrying an Ndufs4lox/lox gene, adeno-associated virus expressing Cre recombinase was injected into regions of the brain ...
Renjini Ramadasan-Nair +5 more
doaj +1 more source
Scientia Pharmaceutica, 2021 Coronavirus Disease 2019 (COVID-19) has spread globally with the number of cases exceeding seventy million. Although trials on potential treatments of COVID-19 Acute Respiratory Distress Syndrome (ARDS) are promising, the introduction of an effective ...
Aiman Suleiman +9 more
doaj +1 more source
High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
, 2018 BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E. +12 more
core +1 more source
Volatile anesthetics alter protein stability
Toxicology Letters, 1998 1. We have used differential scanning calorimetry to measure the halothane induced change in stability of five lipid-free proteins in aqueous solution. 2. The temperature at peak heat capacity (Tm) as the sample is heated provides a measure of stability. 3.
J W, Tanner +2 more
openaire +2 more sources
Inhibition of firefly luciferase by general anesthetics: effect on in vitro and in vivo bioluminescence imaging. [PDF]
PLoS ONE, 2012 UNLABELLED: Bioluminescence imaging is routinely performed in anesthetized mice. Often isoflurane anesthesia is used because of its ease of use and fast induction/recovery.
Marleen Keyaerts +7 more
doaj +1 more source
Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices
Advanced Science, EarlyView.This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee +4 more
wiley +1 more source
Surgical site infection after colorectal surgery according to the main anesthetic agent: a retrospective comparison between volatile anesthetics and propofol [PDF]
Korean Journal of Anesthesiology, 2016 BackgroundAnesthetic agents used for general anesthesia are emerging possible influential factors for surgical site infection (SSI). In this retrospective study, we evaluated the incidence of SSI after colorectal surgery according to the main anesthetic ...
Bon-Wook Koo +6 more
doaj +1 more source
Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]
, 2003 Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong +6 more
core +1 more source