PLoS ONE, 2020 We evaluated whether volatile anesthetics can improve the postoperative outcomes of non-cardiac surgery in patients with preoperative myocardial injury defined by the cardiac troponin elevation.
Jungchan Park +7 more
doaj +2 more sources
BMC Oral Health, 2021 Background A better understanding of the risk factors for postoperative nausea and vomiting (PONV) could improve patient outcomes. This study aimed to analyze the risk factors for PONV and its onset after third molar impaction surgery, and to demonstrate
Hiroaki Hasegawa +4 more
doaj +1 more source
The Power of Education to Reduce the Carbon Footprint of Volatile Anesthetics in Clinical Practice. [PDF]
Anesth AnalgBACKGROUND: Due to their chemical nature as fluorinated hydrocarbon compounds, volatile anesthetics are highly potent greenhouse gases, with desflurane having by far the largest CO2-equivalent (CO2e) footprint.
Schwiethal A +5 more
europepmc +2 more sources
Volatile anesthetics influence blood-brain barrier integrity by modulation of tight junction protein expression in traumatic brain injury. [PDF]
PLoS ONE, 2012 Disruption of the blood-brain barrier (BBB) results in cerebral edema formation, which is a major cause for high mortality after traumatic brain injury (TBI).
Serge C Thal +7 more
doaj +1 more source
OXY-SCORE and Volatile Anesthetics: A New Perspective of Oxidative Stress in EndoVascular Aneurysm Repair-A Randomized Clinical Trial. [PDF]
Int J Mol SciAn aortic aneurysm (AA) is a life-threatening condition. Oxidative stress may be a common pathway linking multiple mechanisms of an AA, including vascular inflammation and metalloproteinase activity.
Burgos-Santamaría A +8 more
europepmc +2 more sources
Low dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus. [PDF]
, 2012 The anesthetic excitement phase occurring during induction of anesthesia with volatile anesthetics is a well-known phenomenon in clinical practice. However, the physiological mechanisms underlying anesthetic-induced excitation are still unclear.
Dodt Hans-Ulrich +29 more
core +1 more source
Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I. [PDF]
PLoS ONE, 2012 Anesthetics are in routine use, yet the mechanisms underlying their function are incompletely understood. Studies in vitro demonstrate that both GABA(A) and NMDA receptors are modulated by anesthetics, but whole animal models have not supported the role ...
Albert Quintana +4 more
doaj +1 more source
Frontiers in Neural Circuits, 2023 BackgroundHow volatile anesthetics work remains poorly understood. Modulations of synaptic neurotransmission are the direct cellular mechanisms of volatile anesthetics in the central nervous system.
Jingxuan Qiu +10 more
doaj +1 more source
Volatile anesthetics suppress glucose-stimulated insulin secretion in MIN6 cells by inhibiting glucose-induced activation of hypoxia-inducible factor 1 [PDF]
PeerJ, 2015 Proper glycemic control is one of the most important goals in perioperative patient management. Insulin secretion from pancreatic β-cells in response to an increased blood glucose concentration plays the most critical role in glycemic control.
Kengo Suzuki +6 more
doaj +2 more sources
Use of Volatile Anesthetics in Extracorporeal Circulation [PDF]
, 2012 Background and objectivesThe use of volatile anesthetics in cardiac surgery is not recent. Since the introduction of halothane in clinical practice, several cardiac surgery centers started to use these anesthetics constantly.ContentIn the last years a ...
Nigro Neto, Caetano +2 more
core +1 more source