Volatile anesthetics affect macrophage phagocytosis. [PDF]
PLoS ONE, 2019 BackgroundPerioperative infections, particularly surgical site infections pose significant morbidity and mortality. Phagocytosis is a critical step for microbial eradication.
Hui Zha +10 more
doaj +3 more sources
Sodium channels as targets for volatile anesthetics
Frontiers in Pharmacology, 2012 The molecular mechanisms of modern inhaled anesthetics although widely used in clinical settings are still poorly understood. Considerable evidence supports effects on membrane proteins such as ligand- and voltage-gated ion channels of excitable cells ...
Karl F. Herold, Hugh C. Hemmings
doaj +2 more sources
Effects of Anesthetics on Barrier Tissue Function
Journal of Immunology Research, 2019 Anesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are ...
Fujing Wang +4 more
doaj +2 more sources
The Differential Effects of Anesthetics on Bacterial Behaviors. [PDF]
PLoS ONE, 2017 Volatile anesthetics have been in clinical use for a long period of time and are considered to be promiscuous by presumably interacting with several ion channels in the central nervous system to produce anesthesia. Because ion channels and their existing
Matthew Chamberlain +5 more
doaj +2 more sources
Nephrotoxicity and Modern Volatile Anesthetics: A Narrative Review [PDF]
ToxicsVolatile anesthetics, while increasingly utilized in intensive care medicine, are associated with significant renal adverse effects. A critical safety concern—particularly with sevoflurane—involves its potential impact on renal function ...
Benedicte Hauquiert +15 more
doaj +2 more sources
Development of a simple method for differential delivery of volatile anesthetics to the spinal cord of the rabbit. [PDF]
PLoS ONE, 2020 Emulsified volatile anesthetic can be directly injected into the circulation and eliminated from blood through lungs. Taking advantage of the unique pharmacokinetics of the emulsified volatile anesthetics, we aimed to develop a less traumatic method to ...
Peng Zhang, Yao Li, Ting Xu
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Volatile anesthetics for lung- and diaphragm-protective sedation. [PDF]
Crit CareThis review explores the complex interactions between sedation and invasive ventilation and examines the potential of volatile anesthetics for lung- and diaphragm-protective sedation.
Müller-Wirtz LM +6 more
europepmc +6 more sources
Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes [PDF]
Clinical Immunology, 2021 Li-Fei Hou +2 more
exaly +2 more sources
Sustainability Standards in Pediatric Anesthesia: Quality Initiative to Reduce Costly Environmentally Harmful Volatile Anesthetics. [PDF]
Pediatr Qual Saf, 2023 BACKGROUND: The emission and entrapment of greenhouse gases (GHG) inside the atmosphere is one of the leading causes of global warming. Commonly administered anesthetics have global warming potential up to 2,000 times greater than carbon dioxide.
Waberski AT +4 more
europepmc +2 more sources
Propofol-Based Anesthesia Maintenance and/or Volatile Anesthetics during Intracranial Aneurysm Repair: A Comparative Analysis of Neurological Outcomes. [PDF]
J Clin Med, 2023 Background: Volatile and intravenous anesthetics have substantial effects on physiological functions, notably influencing neurological function and susceptibility to injury. Despite the importance of the anesthetic approach, data on its relative risks or
Esmaeeli S +13 more
europepmc +2 more sources