Results 1 to 10 of about 17,615 (256)

Relationship between volatile anesthetics and functional outcomes in patients with subarachnoid hemorrhage [PDF]

Journal of Anesthesia, Analgesia and Critical Care
Background Volatile anesthetics have been suggested to exert neuroprotective effects in patients with subarachnoid hemorrhage caused by a ruptured cerebral aneurysm. However, their effects on functional outcomes remain unverified.
Yudai Iwasaki, Kunio Tarasawa, Yu Kaiho, Saori Ikumi, Takahiro Imaizumi, Shizuha Yabuki, Kiyohide Fushimi, Kenji Fujimori, Masanori Yamauchi   +8 more
doaj   +2 more sources

Volatile anesthetics affect macrophage phagocytosis.

PLoS ONE, 2019
BackgroundPerioperative infections, particularly surgical site infections pose significant morbidity and mortality. Phagocytosis is a critical step for microbial eradication.
Hui Zha, Erika Matsunami, Nathan Blazon-Brown, Sophia Koutsogiannaki, Lifei Hou, Weiming Bu, Hasan Babazada, Kirsten C Odegard, Renyu Liu, Roderic G Eckenhoff, Koichi Yuki   +10 more
doaj   +3 more sources

Volatile anesthetics and ischemia-reperfusion injury [PDF]

Korean Journal of Anesthesiology, 2015
Ischemia-reperfusion (IR) injury can occur under various clinical conditions in which the restoration of blood and oxygen to ischemic tissues results in a massive release of oxygen free radicals. For example, cardiac surgery, stroke, tourniquet application for orthopedic surgery, organ transplantation, and restoration of shock can cause IR injury ...
Hong-Beom Bae
doaj   +3 more sources

Sodium channels as targets for volatile anesthetics [PDF]

Frontiers in Pharmacology, 2012
The molecular mechanisms of modern inhaled anesthetics although widely used in clinical settings are still poorly understood. Considerable evidence supports effects on membrane proteins such as ligand- and voltage-gated ion channels of excitable cells ...
Karl F. Herold, Hugh C. Hemmings
doaj   +3 more sources

Volatile anesthetics as a neuroprotective agent [PDF]

Korean Journal of Anesthesiology, 2011
Pharmacologic protection of brain from ischemic insult has been intensively investigated since the early 1960s [1] and a considerable amount of work has been performed to show the effectiveness of various drugs. Among these studies, anesthetic agents, including intravenous and volatile drugs, were shown to be promising agents.
Sungsik Park
doaj   +4 more sources

Prolonged in vitro anti-bacterial, anti-inflammatory, and surfactant-promoting effects of volatile anesthetics [PDF]

BMC Pulmonary Medicine
Background Volatile anesthetics are gaining recognition for their benefits in long-term sedation of mechanically ventilated patients with bacterial pneumonia and acute respiratory distress syndrome.
Claudia Scheffzük, Johanna Lührmann, Robin Brinkmann, Dominika Biedziak, Kristina Gloystein, Patrick Kellner, Cordula Stamme   +6 more
doaj   +2 more sources

Characteristics and Outcomes of Patients Receiving Volatile Anesthetics in Near-Fatal Asthma: A Retrospective Observational Cohort Study [PDF]

Critical Care Explorations
IMPORTANCE AND OBJECTIVES:. Inhaled volatile anesthetics are employed as rescue therapy in near-fatal asthma, despite limited evidence. This study aims to describe the characteristics, management, and outcomes of mechanically ventilated adult patients ...
Christopher Remmington, MPharm, Luigi Camporota, MD, PhD, Daniel Taylor, MD, Angelo Sousa, BSc, Barnaby Sanderson, MSc, Guy Glover, MD   +5 more
doaj   +2 more sources

Volatile anesthetics in the intensive care unit [PDF]

Anaesthesiology Intensive Therapy
The use of volatile anesthetics as an alternative sedation modality in the intensive care unit (ICU) has gained traction over the last several years.
Alexander Morrison-Nozik, Marcin Wąsowicz   +1 more
doaj   +2 more sources

Nephrotoxicity and Modern Volatile Anesthetics: A Narrative Review [PDF]

Toxics
Volatile anesthetics, while increasingly utilized in intensive care medicine, are associated with significant renal adverse effects. A critical safety concern—particularly with sevoflurane—involves its potential impact on renal function ...
Benedicte Hauquiert, Aurelien Gonze, Thibault Gennart, Emily Perriens, Sydney Blackman, Nathan De Lissnyder, Arnaud Robert, Julien Moury, Gauthier Nendumba, Ilann Oueslati, Priscilla Gillis, Ovidiu Vornicu, Anne-Sophie Dincq, Pierre Bulpa, Isabelle Michaux, Patrick M. Honore   +15 more
doaj   +2 more sources

An observational laboratory study to evaluate an anesthetic gas adsorber without anesthetic gas scavenging system [PDF]

BMC Anesthesiology
Background Volatile anesthetics are known to be potent greenhouse gases and a significant source of per-and polyfluoroalkyl substances (PFAS) “forever chemical” pollution.
Katja Nickel, Christian Thoben, Christiane E. Beck, Jan Karsten, Terence Krauß, Alexander Nitschke, Moritz Hitzemann, Stefan Zimmermann, Sebastian Heiderich   +8 more
doaj   +2 more sources