Results 141 to 150 of about 755,676 (359)

Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]

open access: yes, 2003
Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong   +6 more
core   +1 more source

Effect of intravenous anesthetic propofol on synaptic vesicle exocytosis at the frog neuromuscular junction [PDF]

open access: yes, 2014
Aim: To investigate the presynaptic effects of propofol, a short-acting intravenous anesthetic, in the frog neuromuscular junction. Methods: Frog cutaneous pectoris nerve muscle preparations were prepared.
Fonseca, Matheus de Castro   +4 more
core   +1 more source

Anesthetic Techniques and Cancer Recurrence after Surgery

open access: yesThe Scientific World Journal, 2014
Many of the most common anesthetics are used in surgical oncology, yet effects on cancer cells are still not known. Anesthesia technique could differentially affect cancer recurrence in oncologic patients undergoing surgery, due to immunosuppression ...
Vincenzo Fodale   +4 more
doaj   +1 more source

Effects of Inhalation versus Total Intravenous Anesthesia on Postoperative Pulmonary Complications after Anatomic Pulmonary Resection

open access: yesJournal of Chest Surgery, 2022
Background: No consensus exists regarding whether volatile anesthetics are superior to intravenous anesthetics for reducing postoperative pulmonary complications (PPCs) in patients undergoing general anesthesia for surgery.
Soojin Lee   +4 more
doaj   +1 more source

Controlling Level of Unconsciousness by Titrating Propofol with Deep Reinforcement Learning [PDF]

open access: yesarXiv, 2020
Reinforcement Learning (RL) can be used to fit a mapping from patient state to a medication regimen. Prior studies have used deterministic and value-based tabular learning to learn a propofol dose from an observed anesthetic state. Deep RL replaces the table with a deep neural network and has been used to learn medication regimens from registry ...
arxiv  

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

Editorial: Impact of anesthetics on cancer behavior and outcome

open access: yesFrontiers in Pharmacology, 2022
Jui-An Lin   +13 more
doaj   +1 more source

Total intravenous anesthesia using remimazolam for patients with heart failure with reduced ejection fraction: a case series [PDF]

open access: yesKosin Medical Journal
Patients with heart failure undergoing surgery that requires general anesthesia face substantial perioperative risks; however, clear guidelines are not available for anesthesia management in patients with a reduced left ventricular ejection fraction ...
Jimin Lee   +5 more
doaj   +1 more source

Nerves and Anesthesia: A physics perspective on medicine [PDF]

open access: yesAnestezjologia i Ratownictwo 2014; 8: 252-263, 2014
We present a recent theory for nerve pulse propagation and anesthesia and argue that both nerve activity and the action of anesthetics can be understood on the basis of simple physical laws. It was found experimentally that biological membranes melt from a solid state to a liquid state just below physiological temperature. Such melting processes have a
arxiv  

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