Results 161 to 170 of about 736,541 (316)

Effects of Lidocaine on Reducing the Need for Anesthetic Drugs during Ophthalmologic Surgeries

مجله دانشکده پزشکی اصفهان, 2013
Background: The most common postoperative complications are pain, vomiting, and nausea. They may in turn lead to other complications such as wound damage. On the other hand, the use of opioid analgesics has unwanted effects on patients.
Hassan Ali Soltani, Maryam Nasr, Zahra Dana Siadat   +2 more
doaj  

Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du, Xu Liu, Jianghua Shen, Hailong Yuan, Hao Zhang, Gan Xi, Yujing Li, Yuhan Wang, Jiahe Zhang, Chaofan Yang, Pengfei Xu, Jiawan Wang, Fang Wang, Siqi Liu, Yanan Zhou, Qi Gu, Jingjing Lu, Tuo Wei, Zeyu Gao, Jingyi Zang, Jun Wang, Moshi Song   +21 more
wiley   +1 more source

Preparation of gastrodin‐modified dendrimer‐entrapped gold nanoparticles as a drug delivery system for cerebral ischemia–reperfusion injury

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective This study sought to evaluate the feasibility of multifunctional gastrodin (GAS)‐containing nano‐drug carrier system against cerebral ischemia–reperfusion injury (CIRI). Methods The drug‐loaded nanocomposite (Au‐G5.NHAc‐PS/GAS) with certain encapsulation efficiency (EE) was prepared by physical adsorption method using different ...
Wenqiang Huang, Lanlin Wang, Yanghong Zou, Xiangqian Ding, Xin Geng, Jinghui Li, Hexiang Zhao, Renli Qi, Shipeng Li   +8 more
wiley   +1 more source

Dual‐Atom Catalyst Au@S‐rGO for Rapid and Highly Sensitive Electrochemical Detection of Fentanyl in Serum

Advanced Science, EarlyView.
This study develops an Au/S‐doped reduced graphene oxide (Au@S‐rGO) sensor for rapid fentanyl detection. DFT simulations and structural analysis confirm atomically dispersed Au/S configurations, enhancing catalytic activity. The sensor achieves a 9.7 nmol L−1 detection limit, 98–104% recovery in human serum, and 85.7–93.6% consistency with mass ...
Meng Li, ZhiJin Fan, Qiuxia Gao, Ying He, Anyun Xu, Zhaofeng Gu, Shixiong Wang, Huiping Bai, Yuhui Liao, Ruilin Zhang   +9 more
wiley   +1 more source

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Bone construction surgery: A case report using recombinant human platelet‐derived growth factor‐BB

Clinical Advances in Periodontics, Volume 12, Issue 4, Page 262-269, December 2022., 2022
Abstract Background The position and condition of bone largely sets the stage for functional and esthetic implant success. In bone construction surgery, creating a sustainable functional matrix is complex, but necessary, to enable long‐term mechanotransduction and maintenance of soft tissue support.
George A. Mandelaris, Bradley DeGroot
wiley   +1 more source

Highly Absorbent Ultrafast Self‐Gelling Starch Microparticles for Robust Wet‐Tissue Adhesion and Instant Hemostasis

Advanced Science, EarlyView.
The aldehyde‐ and catechol‐modified starch (ACS) microparticle (MP) is developed by chemical modifications and freeze‐milling after calcium intercalation for highly absorbent and tissue‐adhesive properties. The ACS‐MP can be self‐gelled upon contact with biological fluids and blood on tissue surfaces, rapidly absorbing them and achieving robust wet ...
Soohwan An, Jihoon Jeon, Seung Yeop Han, Mi Jeong Lee, Tae‐Gyeong Oh, Eun Je Jeon, Dong Jin Joo, Seung‐Woo Cho   +7 more
wiley   +1 more source

Interactions Between Anesthesia and Sleep: Optimizing Perioperative Care to Improve Sleep Quality and Surgical Recovery Outcomes. [PDF]

Cureus
Patel S, Ownby R.
europepmc   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source

A Neutral and Stable Macrocyclic Mn(II) Complex for MRI Tumor Visualization

ChemMedChem, Volume 17, Issue 24, December 16, 2022., 2022
Research on contrast agents for magnetic resonance imaging has recently guided efforts toward paramagnetic Mn(II) and Fe(III) complexes as alternatives to the well‐established Gd(III)‐based agents regularly used in clinical settings.The new neutral Mn(II) complex MnDO2AMGly reported herein shows good relaxometric performance, no toxicity, and in vivo ...
Loredana Leone, Annasofia Anemone, Antonella Carella, Elena Botto, Dario Livio Longo, Lorenzo Tei   +5 more
wiley   +1 more source