Results 181 to 190 of about 736,541 (316)

Near‐Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer

Aggregate, EarlyView.
A near‐infrared organic room temperature phosphorescence probe of fibroblast‐activation protein in liver cancer microenvironment is prepared to accurately locate liver cancer and determine surgical margins, aiming at guiding hepatectomy and achieving accurate liver cancer resection.
Jinghua Li, Juqing Gu, Liangxuan Ding, Xiaomian Li, Peng Xia, Fusheng Liu, Xi Chen, Weijie Ma, Yong He, Qianqian Li, Zhen Li, Yufeng Yuan   +11 more
wiley   +1 more source

High doses of zoledronic acid induce differential effects on femur and jawbone microstructure

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1487-1495, December 2022., 2022
Abstract Objectives The aim of this study is to investigate the long‐term effects on jaw and femur bone induced by oncologic doses of zoledronic acid in a young rat model. Material and Methods Six 12‐week‐old male Wistar rats received zoledronic acid (0.6 mg/kg) and six control rats received saline solution in the same volume.
Mariana Q. S. Soares, Jeroen Van Dessel, Reinhilde Jacobs, Gustavo Z. Ferreira, Paulo Sérgio da Silva Santos, Laura F. P. Nicolielo, Marco A. H. Duarte, Izabel R. F. Rubira‐Bullen   +7 more
wiley   +1 more source

Review of the Interactions Between Anesthetic Agents and Chemotherapeutic Agents in Cancer Cell Lines Studied In Vitro. [PDF]

Med Sci Monit
Radkowski P, Oniszczuk H, Opolska J, Pawluczuk M, Gowkielewicz M, Grabarczyk Ł.   +5 more
europepmc   +1 more source

A novel pilot animal model for bone augmentation using osseous shell technique for preclinical in vivo studies

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1331-1340, December 2022., 2022
Abstract Objectives Bone grafting is commonly used to reconstruct skeletal defects in the craniofacial region. Several bone augmentation models have been developed to evaluate bone formation using novel bone substitute materials. The aim of this study was to evaluate a surgical animal model for establishing a three‐dimensional (3D) grafting environment
Mohammad Kamal, Sara Al‐Obaidly, Bernd Lethaus, Alexander K. Bartella   +3 more
wiley   +1 more source

Anesthetics change the oral microbial composition of children and increase the abundance of the genus Haemophilus. [PDF]

Transl Pediatr
Xie D, Zhang N, Hu Y, Li Q, Yang Y, Zou Y, Lu Y, Hu W, Guo L, Li H.   +9 more
europepmc   +1 more source

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

Animal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao, Binger Lu, Jinhua Yang, Xiaowan Wang, Shuxian Li, Hongbo Fu, Fenfei Gao   +6 more
wiley   +1 more source

Effect of Intravenous Lidocaine on Rocuronium: A Randomized Controlled Trial. [PDF]

Kobe J Med Sci
Takebe S, Taguchi S, Obata N, Mizobuchi S.   +3 more
europepmc   +1 more source

Development and validation of BCG vaccine‐induced novel granulomatous liver injury preclinical animal model

Animal Models and Experimental Medicine, EarlyView.
The study successfully developed and validated a granulomatous liver injury model using a high‐dose BCG vaccine, simulating hepatic tuberculosis and autoimmune granulomatous liver diseases. Pharmacokinetic analysis examined the metabolic behavior of first‐line antitubercular drugs (isoniazid and rifampicin) and their main metabolites under conditions ...
Swati Sharma, Abhishek Moudgil, Jyoti Grewal, Pankaj Khatri, Vishal Sharma, Madhumita Premkumar, Amanjit Bal, Dibyajyoti Banerjee, Amol N. Patil   +8 more
wiley   +1 more source

The Infratrochlear Nerve Block Reduces the Incidence of Postoperative Nausea Vomiting in Pediatric Patients Undergoing Strabismus Surgery-A Retrospective Study. [PDF]

Biomedicines
Oh CS, Shin HJ, Park SJ, Kim SH, Lee YJ.
europepmc   +1 more source

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

Animal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang, Salma Althobaiti, Braeden Pinkerton, Xin Fu, Zhenshan Jia, Kirk W. Foster, Geoffrey M. Thiele, Troy J. Plumb, Dong Wang   +8 more
wiley   +1 more source