Results 11 to 20 of about 736,541 (316)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

The Potential Effect of General Anesthetics in Cancer Surgery: Meta-Analysis of Postoperative Metastasis and Inflammatory Cytokines

Cancers, 2023
Simple Summary This meta-analysis examined the effect of general anesthetics on metastasis and recurrence after cancer surgery from clinical and pre-clinical studies.
Ru Li, Mousumi Beto Mukherjee, Zhaosheng Jin, Hengrui Liu, Kevin Lin, Qiuyue Liu, J. Dilger, Jun Lin   +7 more
semanticscholar   +1 more source

Cardiac output and the pharmacology of general anesthetics: a narrative review

Colombian Journal of Anesthesiology, 2023
The relationship between cardiac output and anesthetic drugs is important to anesthesiologists, since cardiac output determines the speed with which a drug infused into the bloodstream reaches its target and the intensity of the drug’s effect.
Elena Simón-Polo, Jose Vicente Catalá-Ripoll, José Ángel Monsalve-Naharro, Manuel Gerónimo-Pardo   +3 more
doaj   +1 more source

Inhaled Anesthetics: Environmental Role, Occupational Risk, and Clinical Use

Journal of Clinical Medicine, 2021
Inhaled anesthetics have been in clinical use for over 150 years and are still commonly used in daily practice. The initial view of inhaled anesthetics as indispensable for general anesthesia has evolved during the years and, currently, its general use ...
Mariana Gaya da Costa, A. Kalmar, M. Struys   +2 more
semanticscholar   +1 more source

Arrangements of the intravenous parallel infusions with anti-reflux valves decreasing occlusion alarm delay [PDF]

Korean Journal of Anesthesiology, 2014
BackgroundThe methods of arrangement of combined intravenous parallel infusions using anti-reflux valve (ARV), with and without anti-syphon valve (ASV) that could decrease occlusion alarm delay were investigated.MethodsOcclusion challenge tests were ...
Han Bum Joe, Bong-Ki Moon, Yeon-Ju Lee, Sang-Kee Min   +3 more
doaj   +1 more source

Volatile Anesthetics versus Total Intravenous Anesthesia for Cardiac Surgery

New England Journal of Medicine, 2019
BACKGROUND Volatile (inhaled) anesthetic agents have cardioprotective effects, which might improve clinical outcomes in patients undergoing coronary‐artery bypass grafting (CABG).
G. Landoni, V. Lomivorotov, C. N. Neto, F. Monaco, V. Pasyuga, N. Bradic, R. Lembo, Gordana Gazivoda, V. Likhvantsev, C. Lei, Andrey Lozovskiy, N. Di Tomasso, N. Bukamal, F. S. Silva, A. Bautin, Jun Ma, M. Crivellari, A. Farag, Nikolay Uvaliev, C. Carollo, M. Pieri, J. Kunstýř, Chew-Yin Wang, A. Belletti, L. Hajjar, E. Grigoryev, F. Agrò, H. Říha, M. El-Tahan, M. Scandroglio, Abeer M. Elnakera, M. Baiocchi, P. Navalesi, V. Shmyrev, Luca Severi, M. Hegazy, G. Crescenzi, Dmitry Ponomarev, L. Brazzi, R. Arnoni, D. Tarasov, M. Jovic, M. Calabró, T. Bove, R. Bellomo, A. Zangrillo   +45 more
semanticscholar   +1 more source

Maternal analgosedation and breastfeeding: guidance for the pediatrician

Journal of Pediatric and Neonatal Individualized Medicine, 2015
As part of analgosedative treatment modalities after delivery (e.g. caesarean related pain, birth related trauma, pre-existing pain syndromes), mothers are treated with different analgosedatives that may also affect the nursing infant.
Karel Allegaert, Johannes N. van den Anker   +1 more
doaj   +1 more source

NF‐kB signaling in cardiomyocytes is inhibited by sevoflurane and promoted by propofol

FEBS Open Bio, 2020
Both inhalational and intravenous anesthetics affect myocardial remodeling, but the precise effect of each anesthetic on molecular signaling in myocardial remodeling is unknown.
Keiko Oda‐Kawashima, Anna S. Sedukhina, Naoki Okamoto, Mariya lytvyn, Kimino Minagawa, Teppei Iwata, Toshio Kumai, Eri Sato, Eiichi Inada, Ayako Yamaura, Miki Sakamoto, Marta Roche‐Molina, Juan A. Bernal, Ko Sato   +13 more
doaj   +1 more source

Anesthetics and long-term survival after cancer surgery—total intravenous versus volatile anesthesia: a retrospective study

BMC Anesthesiology, 2019
BackgroundIntravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed to analyze data regarding the relation between anesthetics and the prognosis of cancer patients in our hospital ...
B. Hong, Sunyeul Lee, Yeojung Kim, Minhee Lee, A. Youn, Hyun Rhim, Seokhwan Hong, Y. Kim, S. Yoon, C. Lim   +9 more
semanticscholar   +1 more source

Intravenous ganaxolone for the treatment of refractory status epilepticus: Results from an open‐label, dose‐finding, phase 2 trial

Epilepsia, 2022
Patients with refractory status epilepticus (RSE) have failed treatment with benzodiazepines and ≥1 second‐line intravenous (IV) antiseizure medication (ASM).
H. Vaitkevicius, R. Ramsay, Christa B. Swisher, A. Husain, A. Aimetti, M. Gąsior   +5 more
semanticscholar   +1 more source