Electroconvulsive therapy (ECT) is the treatment method widely used in psychiatric disorders such as depression, bipolar disorder, schizophrenia and schizoaffective disorder.
Rafał Wojdacz+2 more
semanticscholar +1 more source
BackgroundPostoperative cognitive dysfunction (POCD) is a postoperative complication that often occurs in the elderly. This systematic review and meta-analysis aimed to compare intravenous anesthetics (propofol) with inhalation anesthetics (sevoflurane ...
Leilei Huang, Yong Zhang
doaj +1 more source
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.+5 more
core +1 more source
A mini-review of the effects of inhalational and intravenous anesthetics on oxidative stress in dogs
General anesthesia increases the production of reactive oxygen species (ROS), which can exacerbate or increase oxidative stress and thus affect the prognosis of surgical procedures.
Katerina Tomsič, Alenka Nemec Svete
doaj +1 more source
Stabilizing membrane domains antagonizes n-alcohol anesthesia [PDF]
Diverse molecules induce general anesthesia with potency strongly correlated both with their hydrophobicity and their effects on certain ion channels. We recently observed that several n-alcohol anesthetics inhibit heterogeneity in plasma membrane derived vesicles by lowering the critical temperature ($T_c$) for phase separation.
arxiv +1 more source
Liquid general anesthetics lower critical temperatures in plasma membrane vesicles [PDF]
A large and diverse array of small hydrophobic molecules induce general anesthesia. Their efficacy as anesthetics has been shown to correlate both with their affinity for a hydrophobic environment and with their potency in inhibiting certain ligand gated ion channels.
arxiv +1 more source
On the action potential as a propagating density pulse and the role of anesthetics [PDF]
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings on nerves that are not contained in this classical theory. Particularly striking is the finding of reversible heat changes, thickness and phase changes of the membrane during ...
arxiv +1 more source
Neuroprotective effects of intravenous anesthetics: a new critical perspective.
Perioperative cerebral damage can result in various clinical sequela ranging from minor neurocognitive deficits to catastrophic neurological morbidity with permanent impairment and death.
F. Bilotta+4 more
semanticscholar +1 more source
Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]
● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa+4 more
core +2 more sources
The thermodynamics of lipid ion channel formation in the absence and presence of anesthetics. BLM experiments and simulations [PDF]
It is known that lipid membranes become permeable in their melting regime. In microscopic conductance measurements on black lipid membranes one finds that conduction takes place via quantized events closely resembling those reported for protein ion channels. Here, we present data of ion currents through black lipid membranes in the presence and absence
arxiv +1 more source