Lipid Emulsion in the Successful Resuscitation of Local Anesthetic Toxicity after Ankle Block [PDF]
Unexpected occurrence of local anesthetic toxicity is not rare and can cause fatal complications that do not respond to any known drug of intervention.
Sang Hee Park +5 more
doaj +1 more source
Metabifurcation analysis of a mean field model of the cortex
Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space capturing ...
Bojak, Ingo +3 more
core +2 more sources
Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
core +2 more sources
Spin-Mediated Consciousness Theory: An Approach Based On Pan-Protopsychism [PDF]
As an alternative to our original dualistic approach, we present here our spin-mediated consciousness theory based on pan-protopsychism. We postulate that consciousness is intrinsically connected to quantum mechanical spin since said spin is embedded in ...
Hu, Huping, Wu, Maoxin
core
Melting transitions in biomembranes
We investigated melting transitions in biological membranes in their native state that include their membrane proteins. These membranes originated from \textit{E. coli}, \textit{B.
Heimburg, Thomas +5 more
core +1 more source
A local anesthetic, ropivacaine, suppresses activated microglia via a nerve growth factor-dependent mechanism and astrocytes via a nerve growth factor-independent mechanism in neuropathic pain [PDF]
Background Local anesthetics alleviate neuropathic pain in some cases in clinical practice, and exhibit longer durations of action than those predicted on the basis of the pharmacokinetics of their blocking effects on voltage-dependent sodium channels ...
Sakamoto Atsuhiro +4 more
core +1 more source
Effects of Gabaergic phenols on phospholipid bilayers as evaluated by 1H-NMR [PDF]
The phenols propofol and thymol, and lately carvacrol, eugenol and chlorothymol, have been shown to act as positive allosteric modulators on GABAA receptor, which is the main inhibitory receptor of the central nervous system.
Fraceto, Leonardo Fernandes +4 more
core +1 more source
"Lidocaine anaphylaxis after epidural anesthesia for cesarean section " [PDF]
Allergic reaction to local anesthetics is very rare and most of the reported cases are due to ester local anesthetics. This case presents a parturient who experienced cardiac arrest due to hypersensitivity reaction to lidocaine after epidural injection ...
Setayesh AR
doaj +1 more source
Li Zhang,1,* Yirui Hu,2,* Xianren Wu,1 Michael J Paglia,3 Xiaopeng Zhang1 1Department of Anesthesiology, Geisinger Medical Center, Danville, PA, USA; 2Population Health Sciences, Geisinger Medical Center, Danville, PA, USA; 3Department of Obstetrics and ...
Zhang L, Hu Y, Wu X, Paglia MJ, Zhang X
doaj
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A. +5 more
core +1 more source

