Safety of local anesthetics, [PDF]
Anais Brasileiros de Dermatologia, 2020 Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types.
Ana Carolina Figueiredo Pereira Cherobin +1 more
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Effects of simultaneous administration of local anesthetics on seizure induced threshold: an experimental study in rats [PDF]
BMC AnesthesiologyBackground The effect of the simultaneous administration of local anesthetics, whether synergistic, additive, or antagonistic, has not yet been established.
Yoshie Noji +5 more
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Comparative effectiveness of nerve block strategies for preventing postherpetic neuralgia in thoracic herpes zoster: a network meta-analysis [PDF]
Frontiers in NeurologyBackgroundShingles is a common global disease, with the chest region being one of its most frequently affected areas. Postherpetic neuralgia (PHN) is one of the most common and debilitating complications of this disease, characterized by high incidence ...
Wensheng Lu +4 more
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Mydriasis mediated by local anesthetics: an unexpected adverse event or new therapeutic indication? [PDF]
Therapeutic Advances in Drug SafetyThe increasing off-label use of medications needs a robust pharmacovigilance system. This is particularly crucial given the abundance of scientific data that can be harnessed to ensure a product’s safety.
Homero Contreras-Salinas +4 more
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The 90% minimum effective volume and concentration of lidocaine for ultrasound-guided stellate ganglion blocks in adults: a biased-coin design, up-and-down sequential allocation trial [PDF]
Korean Journal of AnesthesiologyBackground As ultrasound imaging technology matured, stellate ganglion blocks (SGBs) have become increasingly precise and safe, and their use in clinical practice has become widespread. However, the 90% minimum effective volume (MEV90) and concentration (
Shujun Sun +8 more
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Research advances in the roles of local anesthetics in tumor metastasis and recurrence [PDF]
Jichu yixue yu linchuang, 2022 Anesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer.
LIU Chang, GUO Xiang-yang
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Direct Cytotoxic and Indirect, Immune-Mediated Effects of Local Anesthetics Against Cancer
Frontiers in Oncology, 2022 Local anesthetics are frequently employed during surgery in order to control peri- and postoperative pain. Retrospective studies have revealed an unexpected correlation between increased long-term survival and the use of local anesthetics during ...
Alejandra Wu Chuang +9 more
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Stem Cell Research & Therapy, 2021 Background A large number of preclinical studies have shown that local anesthetics have a direct inhibitory effect on tumor biological activities, including cell survival, proliferation, migration, and invasion. There are few studies on the role of local
Xiaoqing Fan +7 more
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BMC Anesthesiology, 2020 Background Retrospective analysis and pre-clinical studies suggest that local anesthetics have anti-tumoral effects. However, the association between cancer recurrence and the use of local anesthesia is inconclusive and most reports are based on single ...
Guanhua Zhu +3 more
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Analgesic protocol for procedural pain treatment of second-degree burns in children [PDF]
Vojnosanitetski Pregled, 2023 Background/Aim. Children with burns are submitted to multiple painful and anxiety-related procedures during the change of wound dressing, treatment, and rehabilitation.
Komarčević Aleksandar +4 more
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