Results 1 to 10 of about 75,087 (309)

Lipid Emulsion in the Successful Resuscitation of Local Anesthetic Toxicity after Ankle Block [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2014
Unexpected occurrence of local anesthetic toxicity is not rare and can cause fatal complications that do not respond to any known drug of intervention.
Sang Hee Park   +5 more
doaj   +1 more source

Metabifurcation analysis of a mean field model of the cortex

open access: yes, 2010
Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space capturing ...
Bojak, Ingo   +3 more
core   +2 more sources

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]

open access: yes, 2008
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A.   +3 more
core   +2 more sources

Spin-Mediated Consciousness Theory: An Approach Based On Pan-Protopsychism [PDF]

open access: yes, 2002
As an alternative to our original dualistic approach, we present here our spin-mediated consciousness theory based on pan-protopsychism. We postulate that consciousness is intrinsically connected to quantum mechanical spin since said spin is embedded in ...
Hu, Huping, Wu, Maoxin
core  

Melting transitions in biomembranes

open access: yes, 2019
We investigated melting transitions in biological membranes in their native state that include their membrane proteins. These membranes originated from \textit{E. coli}, \textit{B.
Heimburg, Thomas   +5 more
core   +1 more source

A local anesthetic, ropivacaine, suppresses activated microglia via a nerve growth factor-dependent mechanism and astrocytes via a nerve growth factor-independent mechanism in neuropathic pain [PDF]

open access: yes, 2011
Background Local anesthetics alleviate neuropathic pain in some cases in clinical practice, and exhibit longer durations of action than those predicted on the basis of the pharmacokinetics of their blocking effects on voltage-dependent sodium channels ...
Sakamoto Atsuhiro   +4 more
core   +1 more source

Effects of Gabaergic phenols on phospholipid bilayers as evaluated by 1H-NMR [PDF]

open access: yes, 2013
The phenols propofol and thymol, and lately carvacrol, eugenol and chlorothymol, have been shown to act as positive allosteric modulators on GABAA receptor, which is the main inhibitory receptor of the central nervous system.
Fraceto, Leonardo Fernandes   +4 more
core   +1 more source

"Lidocaine anaphylaxis after epidural anesthesia for cesarean section " [PDF]

open access: yesActa Medica Iranica, 2001
Allergic reaction to local anesthetics is very rare and most of the reported cases are due to ester local anesthetics. This case presents a parturient who experienced cardiac arrest due to hypersensitivity reaction to lidocaine after epidural injection ...
Setayesh AR
doaj   +1 more source

A Systematic Review and Meta-Analysis of Randomized Controlled Trials of Labor Epidural Analgesia Using Moderately High Concentrations of Plain Local Anesthetics versus Low Concentrations of Local Anesthetics with Opioids

open access: yesJournal of Pain Research, 2021
Li Zhang,1,* Yirui Hu,2,* Xianren Wu,1 Michael J Paglia,3 Xiaopeng Zhang1 1Department of Anesthesiology, Geisinger Medical Center, Danville, PA, USA; 2Population Health Sciences, Geisinger Medical Center, Danville, PA, USA; 3Department of Obstetrics and ...
Zhang L, Hu Y, Wu X, Paglia MJ, Zhang X
doaj  

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

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