Characterization of the Community Structure of Large-Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]
arXiv, 2016 One of the main goals of neuroscience is to understand how an organism's cognitive capacities or physiological states are potentially related to brain activities that involve the interaction of multiple brain structures and cortical areas. A key feature of functional brain networks is that they are modularly structured, and this modular architecture is
arxiv
Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation [PDF]
, 2018 Propofol is widely used in the clinic for the induction and maintenance of general anesthesia. As with most general anesthetics, however, our understanding of its mechanism of action remains incomplete.
Carnevale, Vincenzo +4 more
core +1 more source
Use of Local Anesthetics Associated with Vasoconstrictors in Dentistry. Is it a Safe Treatment? A Literature Update [PDF]
, 2020 The use of local anesthetics associated with vasoconstrictors offers advantages and disadvantages associated to its sympathomi- metic effect and it should be considered during the dental treatment.
González Navarro, Beatriz +4 more
core
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
Effect of Dibucaine on Phase Behavior of Ternary Liposome [PDF]
Med. Chem. Commun. 6, 1444-1451 (2015), 2014 We investigated the effect of Dibucaine hydrochloride (DC$\cdot$HCl), one of the local anesthetics, on phase behavior of ternary liposome composed of dioleoylphosphatidylcholine (DOPC), dipalmitoylphosphatidylcholine (DPPC), and cholesterol (Chol). The large DOPC/DPPC/Chol liposome, that is directly observable by optical microscope, is commonly known ...
arxiv
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
Advanced Materials, EarlyView.The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang +12 more
wiley +1 more source
Advanced Materials, EarlyView.Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim +8 more
wiley +1 more source
The use of tricaine methanesulfonate, clove oil, metomidate, and 2-phenoxyethanol for anesthesia induction in alewives (Alosa pseudoharengus) [PDF]
, 2015 Anesthetics are widely used in routine aquaculture operations to immobilize animals for tagging, spawning, handling, and vaccination. A number of anesthetics are currently available for finfish, but their efficacy and optimal dosage is highly species ...
Watson, Mark Thomas
core +2 more sources
Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
Advanced Materials, EarlyView.A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung +10 more
wiley +1 more source
LOCAL ANESTHETICS INDUCED ALLERGIC REACTIONS AND CONFOUNDING FACTORS
Romanian Journal of Oral Rehabilitation, 2019 The local anesthetics (LAs) immediate-type allergy is considered extremely rare by allergists. However, many health care practitioners and patients overestimate the risk of LA allergy and its potential of cross-reactivity.
Andrei Gheorghe Vicovan +4 more
doaj