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Best Practice & Research Clinical Anaesthesiology, 2018 Local anesthetics are used for performing various regional anesthesia techniques to provide intraoperative anesthesia and analgesia, as well as for the treatment of acute and chronic pain. Older medications such as lidocaine and bupivacaine as well as newer ones such as mepivacaine and ropivacaine are being used successfully for decades.
Shah, Jarna +2 more
semanticscholar +5 more sources
Current Opinion in Anaesthesiology, 2010 Local anesthetics are not only used as drugs to block the sodium channel to provide analgesia and antiarrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs.Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to ...
Borgeat, A, Aguirre, J
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Local Anesthetics, Local Anesthetic Systemic Toxicity (LAST), and Liposomal Bupivacaine.
Clinics in Sports Medicine, 2022Local anesthetics have played a vital role in the multimodal analgesia approach to patient care by decreasing the use of perioperative opioids, enhancing patient satisfaction, decreasing the incidence of postoperative nausea and vomiting, decreasing the ...
Michael O On'Gele +3 more
semanticscholar +1 more source
Potential Therapeutic Application of Local Anesthetics in Cancer Treatment.
Recent Patents on Anti-Cancer Drug Discovery, 2022Local anesthetics are voltage-gated sodium channel blockers primarily administered locally or to the innervating nerves for anesthetic or analgesic purposes. In vitrol studies have found direct effects of local anesthetics on cancer cell, such as impacts
Zhaosheng Jin +6 more
semanticscholar +1 more source
Journal of PeriAnesthesia Nursing, 2007
Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. This chapter, on the analgesic aspects of local anesthetics, reviews their broad actions that affect many different molecular targets and disrupt their functions in pain processing.
F, Yanagidate, G R, Strichartz
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Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. This chapter, on the analgesic aspects of local anesthetics, reviews their broad actions that affect many different molecular targets and disrupt their functions in pain processing.
F, Yanagidate, G R, Strichartz
openaire +5 more sources
Dermatologic Surgery, 1996
Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use of local anesthetic agents.This article reviews nerve physiology, pharmacology, classification of local ...
R A, Skidmore +2 more
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Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use of local anesthetic agents.This article reviews nerve physiology, pharmacology, classification of local ...
R A, Skidmore +2 more
openaire +4 more sources
Effects of local anesthetics on cancer cells.
Pharmacology and Therapeutics, 2020Local anesthetics are widely used during clinical cancer surgeries. Studies have suggested that the use and the type of anesthesia affect cancer outcomes.
Hengrui Liu, J. Dilger, Jun Lin
semanticscholar +1 more source
Chondrotoxic Effects of Local Anesthetics on Human Knee Articular Cartilage: A Systematic Review
PM & R : the journal of injury, function, and rehabilitation, 2019To review the current literature on the effects of intraarticular local anesthetics on human knee articular cartilage.
P. Jayaram +3 more
semanticscholar +1 more source
Annals of Emergency Medicine, 1985
Local anesthetics are remarkably useful agents that enhance patient comfort and improve patient compliance. Their use, however, requires an understanding of their action, proper dosages, potential risks, and treatment of reactions. We have presented the history, pharmacokinetics, action, risks of using, and ways in which agents are used to treat the ...
R S, Altman +2 more
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Local anesthetics are remarkably useful agents that enhance patient comfort and improve patient compliance. Their use, however, requires an understanding of their action, proper dosages, potential risks, and treatment of reactions. We have presented the history, pharmacokinetics, action, risks of using, and ways in which agents are used to treat the ...
R S, Altman +2 more
openaire +2 more sources