Results 71 to 80 of about 310,289 (342)

Comparison of the efficacy of saline, local anesthetics, and steroids in epidural and facet joint injections for the management of spinal pain: A systematic review of randomized controlled trials

Surgical neurology international, 2015
Background: The efficacy of epidural and facet joint injections has been assessed utilizing multiple solutions including saline, local anesthetic, steroids, and others.
L. Manchikanti, D. Nampiaparampil, Kavita N. Manchikanti, F. Falco, V. Singh, Ramsin M. Benyamin, A. Kaye, N. Sehgal, A. Soin, Thomas T. Simopoulos, S. Bakshi, C. Gharibo, C. Gilligan, J. Hirsch   +13 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Preventive but Not Therapeutic Topical Application of Local Anesthetics Can Inhibit Experimental Epidermolysis Bullosa Acquisita in Mice

Frontiers in Immunology, 2021
Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disorder characterized and caused by autoantibodies against type VII collagen (COL7).
Lifang Wen, Lifang Wen, Xiaoru Dong, Xiaoru Dong, Qing Li, Gabriele Schramm, Bing Zhang, Detlef Zillikens, Ralf J. Ludwig, Frank Petersen, Xinhua Yu   +10 more
doaj   +1 more source

Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]

, 2020
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A., Chen, Ichun Anderson, Cheng, Xiaojun, Erdener, Sefik Evren, Kılıç, Kıvılcım, Kura, Sreekanth, Lee, Blaire Ss, Postnov, Dmitry, Sunil, Smrithi, Tang, Jianbo   +9 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

An emphasis on the wide usage and important role of local anesthesia in dentistry: A strategic review

Dental Research Journal, 2012
Local anesthesia forms the major part of pain-control techniques in dentistry. The prevention and elimination of pain during dental treatment has benefited patients, their doctors and dental hygienists, enabling the dental profession to make tremendous ...
Preetinder Singh
doaj   +1 more source

Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]

, 2018
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek, Akin, Al-Zaben, Alm, Amminnikutty, Amoli, Anderson, Anderson, Antila, Arcioni, Association of Paediatric Anaesthetists of Great Britain and Ireland, Aubrun, Aveline, Aysenur, Bailey, Bailie, Bakan, Baley, Becke, Beers, Bell, Ben-Meir, Bertini, Bhalla, Birmingham, Bouwmeester, Bozkurt, Breitfeld, Breschan, Breschan, Brown, Brown, Büttner, Carstensen, Cha, Chan, Chou, Conti, Cousins, Crellin, Cyna, Dadure, Dadure, Dahi-Taleghani, Dahmani, Dalens, Das, Derry, Derry, Duedahl, Ecoffey, El-Fattah, Elshammaa, Fendrich, Fieler, Finkel, Flack, Fösel, Ganidagli, Gear, Gemma, Ginsberg, Glover, Habre, He, Hicks, Hinz, Holmer Pettersson, Hong, Howard, Hudcova, Huenseler, Huynh, Höhne, Ingelmo, Ivani, Ivani, Ivani, Ivani, Jahr, Jaksch, José María, Ju, Jöhr, Kamata, Kart, Kimiaei Asadi, Kokki, Kokki, Kokki, Kokki, Koppert, Kost-Byerly, Kost-Byerly, Kubica-Cielińska, Kumar, Kurihara, Kwak, Lam, Laskowski, Lavonas, Leclair, Lee, Leksowski, Leoni, Litalien, Liu, Liu, Lorenzo, Lundeberg, Lönnqvist, Lönnqvist, Lönnqvist, Manworren, Marel, Marhofer, Mazoit, McNicol, Merry, Messerer, Messerer, Miller, Miró, Mobley, Mohammed, Momeni, Moriceau, Morton, Morton, Mukherjee, Müller, Mędrzycka-Dąbrowska, O'Sullivan, Olkkola, Orange, Ousley, Pace, Park, Park, Pasero, Petrat, Pierce, Polaner, Qian, Rabbitts, Redmann, Richer, Rugyte, Sahin, Sammartino, Sandeman, Schnabel, Schnabel, Schug, Schug, Schug, Schultz-Machata, Sekhavat, She, Shirazi, Sng, Soh, Sola, Soulard, Southworth, Sowder, Spacek, Splinter, Stamer, Staschen, Steans, Steffen, Subramanyam, Suresh, Taheri, Tobias, Tsuchiya, Valizadeh, Voepel-Lewis, Walker, Walther-Larsen, Walther-Larsen, Wang, Weintraud, Willschke, Willschke, Willschke, Wilson, Wilson-Smith, Wininger, Wong, Wong, Xue, Xue, Yaster, Yildiz, Yung   +196 more
core   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

Aging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang, Yueying Liu, Jing Yang, Tyvette S. Hilliard, Reihaneh Safavi‐Sohi, Daniel D. Hu, Elizabeth I. Harper, Gena Dominique, Wanrui Wang, Jeffrey Johnson, Marwa Asem, William Milosevich, Julia Florek Carlson, Yunpeng Bai, Jinmin Miao, Zhong‐Yin Zhang, Matthew M. Champion, M. Sharon Stack   +17 more
wiley   +1 more source

Malignant hyperthermia – state of knowledge

Journal of Education, Health and Sport, 2022
Malignant hyperthermia (MH) is a relatively rare, but potentially lethal genetic disorder. That disease is characterized by hypermetabolic response of the skeletal muscles caused by exposure to triggering agents e.g. volatile anesthetics or depolarizing
Michał Perszke, Dominika Egierska, Kamil Cieślak, Miłosz Berliński, Witold Świenc, Oskar Tokarczuk, Anna Walendzik   +6 more
doaj   +1 more source

SENSORY REGRESSION TIME FROM SUBARACHNOID BLOCK WITH HYPERBARIC 0.75% BUPIVACAINE IN THE OBESE PATIENT [PDF]

, 1989
The purpose of this study was to determine if obese patients have a different sensory regression time from subarachnoid block than non-obese patients using hyperbaric 0.75% bupivacaine. A quasi-experimental design was used. Twenty patients were separated
Hilton, George Leslie
core   +1 more source