Results 101 to 110 of about 97,243 (292)

FIGO committee opinion: Environmental drivers of obstetric health and early childhood development

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Environmental exposures are increasingly recognized as critical, yet underappreciated, determinants of reproductive, perinatal, and early childhood health. Developed through a structured consensus process and grounded in systematic evidence review, this FIGO committee opinion provides a comprehensive synthesis of the current evidence linking ...
Nathaniel DeNicola, Emily Lasher, Abena BakenRa, Rashmi Joglekar, Jun Zhang, Annette Hasenburg, Krishnendu Gupta, Ditas Decena, Francisco Edna, David Graham, Edward Morris, Blami Dao, Tracey Woodruff   +12 more
wiley   +1 more source

Genomic Alteration Burden in Advanced Prostate Cancer and Therapeutic Implications. [PDF]

, 2019
The increasing number of patients with sequenced prostate cancer genomes enables us to study not only individual oncogenic mutations, but also capture the global burden of genomic alterations.
Bose, Rohit, Ryan, Matthew J
core   +1 more source

Performance of four modern whole genome amplification methods for copy number variant detection in single cells [PDF]

, 2017
Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of cells.
Cornelis, Senne, Deforce, Dieter, Deleye, Lieselot, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Vander Plaetsen, Ann-Sophie   +5 more
core   +1 more source

Efficacy of Fetal Ear Length as a Prenatal Marker of Chromosomal Anomalies: A Prospective, Multicenter Cohort Study in a Southern European Population

Journal of Clinical Ultrasound, EarlyView.
Fetal ear length (FEL) correlates with gestational age and may help detect chromosomal anomalies. This study developed a nomogram for a Southern European population, showing high measurement reliability. While FEL ≤ 5th percentile increased anomaly risk, its moderate sensitivity and specificity limit clinical utility.
Elisabet Baldrich, Montse Comas, Alicia Maldonado, Marcos Blasco, Josep‐Maria Manresa‐Domínguez, Maria Iniguez‐Cruz, Antoni Borrell   +6 more
wiley   +1 more source

Aneuploidy Drives Genomic Instability in Yeast [PDF]

, 2011
Aneuploidy decreases cellular fitness, yet it is also associated with cancer, a disease of enhanced proliferative capacity. To investigate one mechanism by which aneuploidy could contribute to tumorigenesis, we examined the effects of aneuploidy on ...
A. Amon, B. M. George, Chen, Duesberg, H. M. Blank, Harfe, I. L. Brito, J. M. Sheltzer, Lengauer, Lisby, Matzke, Meister, Musacchio, Niwa, O. Niwa, Paques, Pavelka, Rattray, S. J. Pfau, Shaver, Sniegowski, T. J. Humpton, Torres, Torres, Weaver, Williams, Y. Hiraoka, Y. Tange   +27 more
core   +2 more sources

Fetal Tricuspid Annular Plane Systolic Excursion in the Surveillance of Intra‐Abdominal Umbilical Vein Varix

Journal of Ultrasound in Medicine, EarlyView.
Objective To describe the application of tricuspid annular plane systolic excursion (TAPSE) in monitoring cardiac function in cases of fetal intra‐abdominal umbilical vein varix (FIUVV). Methods The sample consisted of all cases of FIUVV diagnosed in a tertiary medical center between 2018 and 2023 that were assessed by sonographic fetal TAPSE.
Yossi Geron, Lior Drukker, Sharon Perlman, Ran Matot, Victoria Hermann, Natav Hendin, Ron Bardin, Yinon Gilboa, Ron Charach   +8 more
wiley   +1 more source

Author Correction: Selective advantage of trisomic human cells cultured in non-standard conditions

Scientific Reports, 2022
Samuel D. Rutledge, Temple A. Douglas, Joshua M. Nicholson, Maria Vila-Casadesús, Courtney L. Kantzler, Darawalee Wangsa, Monika Barroso-Vilares, Shiv D. Kale, Elsa Logarinho, Daniela Cimini   +9 more
doaj   +1 more source

Abnormal early cleavage events predict early embryo demise: sperm oxidative stress and early abnormal cleavage. [PDF]

, 2014
Human embryos resulting from abnormal early cleavage can result in aneuploidy and failure to develop normally to the blastocyst stage. The nature of paternal influence on early embryo development has not been directly demonstrated although many studies ...
Barker, Christopher M, Burruel, Victoria, Klooster, Katie, Meyers, Stuart, Pera, Renee Reijo   +4 more
core   +2 more sources

Combining Detailed Fetal Anatomy Scanning in the NT Window Versus Early Second Trimester Scanning at 14–16 Weeks

Journal of Ultrasound in Medicine, EarlyView.
Objectives First‐trimester ultrasound has evolved to incorporate a detailed fetal anatomy scan (FAS) with nuchal translucency (NT) screening. Many institutions use a 2‐visit protocol: NT followed by detailed FAS at 14–16 weeks. We aimed to evaluate whether integrating detailed FAS into the NT window (12 + 5 to 13 + 6 weeks) is non‐inferior in ...
Tomer Shwartz, Sarah M. Cohen, Michal Lipschuetz, Hila Hochler, Yaron Zalel, Dan V. Valsky, Simcha Yagel   +6 more
wiley   +1 more source

The Clinical Significance of Fetal Intra‐Abdominal Umbilical Vein Varix A Comparative Study

Journal of Ultrasound in Medicine, EarlyView.
Objectives To clarify the clinical significance and optimal management of fetal intra‐abdominal umbilical vein varix (FIUVV). Methods A retrospective study comparing composite asphyxia‐related adverse outcomes including stillbirth, cesarean delivery due to non‐reassuring fetal heart rate (CD NRFHR), Apgar <7, Cord pH <7, neonatal intensive care unit ...
Keren Zloto, Ariella Wiener, Natalie Bibar, Raanan Meyer, Abeer Massarwa, Michal Fishel Bartal, Alina Weissmann‐Brenner, Eran Kassif, Tal Weissbach   +8 more
wiley   +1 more source