Results 141 to 150 of about 98,141 (333)

Aneuploidy

Citation: 'aneuploidy' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10394 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

A novel retinoblastoma therapy from genomic and epigenetic analyses. [PDF]

, 2012
Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very quickly following RB1 inactivation but the underlying mechanism is not known.
Bahrami, Armita, Benavente, Claudia A, Brennan, Rachel, Chen, Xiang, Ding, Li, Dooling, David J, Downing, James R, Dyer, Michael A, Dyson, Nicholas J, Easton, John, Ellison, David, Flores-Otero, Jacqueline, Fulton, Lucinda L, Fulton, Robert S, Gupta, Pankaj, Hong, Xin, Lu, Charles, Ma, Jing, Manning, Amity L, Mardis, Elaine R, McEvoy, Justina, Mukatira, Suraj, Mullighan, Charles, Naeve, Clayton, Neale, Geoff, Ochoa, Kerri, Pounds, Stanley, Rusch, Michael, Shurtleff, Sheila, Ulyanov, Anatoly, Wang, Jianmin, Wilson, Matthew, Wilson, Richard K, Wu, Gang, Zhang, Jinghui, Zhao, David   +35 more
core  

Trends in the Use and Indications for Intracytoplasmic Sperm Injection Between 2005 and 2017: A State‐Wide Descriptive Cohort Analysis

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Intracytoplasmic sperm injection (ICSI) was first developed to overcome male factor infertility. ICSI has increased in uptake globally, including in cases where its use is non‐essential for fertilisation. Aims To identify temporal trends in the use of, and indications for ICSI in an Australian context.
Aleah Kink, Parinaz Mehdipour, Richard J. Hiscock, Beverley J. Vollenhoven, Catharyn J. Stern, Susan P. Walker, Mark P. Green, Tiki Osianlis, Franca Agresta, David Wilkinson, Stephen Tong, Roxanne Hastie, Amber L. Kennedy, Anthea C. Lindquist   +13 more
wiley   +1 more source

Genetics of infertility and “assisted fertilization” in the Bible: The case of Abraham and his family

Andrology, EarlyView.
Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni, Frank Tüttelmann, Livio Casarini   +2 more
wiley   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Comparative modeling reveals the molecular determinants of aneuploidy fitness cost in a wild yeast model

Cell Genomics
Summary: Although implicated as deleterious in many organisms, aneuploidy can underlie rapid phenotypic evolution. However, aneuploidy will be maintained only if the benefit outweighs the cost, which remains incompletely understood. To quantify this cost
Julie Rojas, James Hose, H. Auguste Dutcher, Michael Place, John F. Wolters, Chris Todd Hittinger, Audrey P. Gasch   +6 more
doaj   +1 more source

Review for "PGT‐A preimplantation genetic testing for aneuploidies and embryo selection in routine ART cycles: Time to step back?"

, 2020
Simone Palini
openalex   +1 more source

Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer Cells [PDF]

, 2013
Timo Gemoll, Jens K. Habermann, Susanne Becker, Silke Szymczak, Madhvi B. Upender, Hans‐Peter Bruch, Ulf Hellman, Thomas Ried, Gert Auer, Hans Jörnvall, Uwe J. Roblick   +10 more
openalex   +1 more source

Fetal biometry and maternal characteristics for second trimester prediction of stillbirth

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this study of 377 563 singleton pregnancies from the Swedish Pregnancy Register, we find evidence of increased stillbirth risk among fetuses with short mid‐gestational femur length, especially in combination with small abdominal circumference, but not with normal femur length, regardless of other small fetal dimensions.
Linda Lindström, Olof Stephansson, Sven Cnattingius, Allen Wilcox, Michaela Granfors   +4 more
wiley   +1 more source

Human Papillomavirus-Induced Chromosomal Instability and Aneuploidy in Squamous Cell Cancers

Viruses
Chromosomal instability (CIN) and aneuploidy are hallmarks of cancer. CIN is defined as a continuous rate of chromosome missegregation events over the course of multiple cell divisions.
Samyukta Mallick, Yeseo Choi, Alison M. Taylor, Pippa F. Cosper   +3 more
doaj   +1 more source