Induction of aneuploidy, a cluster of babies with Down's syndrome, and a potential danger with in vitro fertilization. [PDF]
Diane Bond
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Infertility is a global concern, with male factors contributing to nearly half of cases. This study compared glycopatterns of sperm and sperm‐derived exosomes from conventional IVF and rescue ICSI (RICSI) patients, revealing key differences in glycan expression.
Muhammad Anas Ramzan+10 more
wiley +1 more source
Non-random Mis-segregation of Human Chromosomes
Summary: A common assumption is that human chromosomes carry equal chances of mis-segregation during compromised cell division. Human chromosomes vary in multiple parameters that might generate bias, but technological limitations have precluded a ...
Joseph Thomas Worrall+9 more
doaj
Evaluation of sensitivity in DNA aneuploidy detection using a mathematical model [PDF]
Neal A. Benson, Raul C. Braylan
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Cytoduction Preserves Genetic Diversity Following Plasmid Transfer Into Pooled Yeast Libraries
Unlike transformation, cytoduction (mating without nuclear fusion) is efficient at introducing plasmids into high‐diversity libraries with minimal impact on population diversity. ABSTRACT Introducing plasmids into yeast is a critical step for many phenotypic assays and genetic engineering applications.
Han‐Ying Jhuang+2 more
wiley +1 more source
Analysis of Aneuploidy in First-Cleavage Mouse Embryos Fertilized in Vitro and in Vivo
Lynn R. Fraser, Ian Maudlin
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Effects of diethylstilbestrol and its methyl ethers on aneuploidy induction and microtubule distribution in Chinese hamster V79 cells [PDF]
Y Sakakibara+7 more
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Interspecific Hybridization and Aneuploidy in the Genus <i>Nicotiana</i>
U. Subhashini
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Significance of c-erb5-2 amplification and DNA aneuploidy. Analysis in 78 patients with node-negative breast cancer [PDF]
Jeannette Babiak+2 more
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CALB1 and RPL23 Are Essential for Maintaining Oocyte Quality and Function During Aging
This study investigates the mechanisms of oocyte aging in mice, identifying Calb1 and Rpl23 as key genes involved in calcium ion homeostasis and mitochondrial function. Knockdown of these genes led to mitochondrial dysfunction, meiotic defects, and spindle assembly abnormalities, while their overexpression partially rescued age‐related oocyte defects ...
Yingxue Han+6 more
wiley +1 more source