New Phytologist, EarlyView.Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Sandrine Bujaldon +3 more
wiley +1 more source
Evolution of AR and Non-AR Alterations in ctDNA of Patients with Metastatic Prostate Cancer Treated in the Phase III Alliance A031201 Trial. [PDF]
Clin Cancer ResValentín López JC +17 more
europepmc +1 more source
Lessons from clinical and genetic characterization of intellectual disability
Developmental Medicine &Child Neurology, EarlyView.
Fuki Marie Hisama
wiley +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, EarlyView.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Maternal age and blastocyst morphology as independent predictors of embryonic euploidy in preimplantation genetic testing cycles: A retrospective cohort study. [PDF]
Medicine (Baltimore)Huang H +5 more
europepmc +1 more source
Advanced Genetics, Volume 7, Issue 3, September 2026.ABSTRACT Programmed DNA double‐strand breaks (DSBs) initiate meiotic recombination at discrete genomic hotspots, and their precise mapping is crucial for understanding the molecular regulation of genome stability and evolution. A variety of genome‐wide methods have been developed, each leveraging different biochemical principles — from direct capture ...
Jianqiang Bao
wiley +1 more source
Improved positive predictive value of non-invasive prenatal testing through integration with second-trimester ultrasound soft markers for fetal chromosomal abnormalities: a retrospective cohort study. [PDF]
Front Endocrinol (Lausanne)Fu D, Wu Q, Ju Y, Jiang M, Zhang S.
europepmc +1 more source
Hematological Oncology, Volume 44, Issue 5, September 2026.ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Marina Pérez‐Aguilera +14 more
wiley +1 more source
Aneuploidy of chromosome 8 promotes the mesenchymal lineage during cell fate transitions. [PDF]
Sci AdvLiang C +10 more
europepmc +1 more source
International Journal of Cancer, Volume 159, Issue 5, Page 1311-1321, 1 September 2026.Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn +13 more
wiley +1 more source