Results 141 to 150 of about 55,696 (242)

Gastric Cancer: Pathobiology and Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu, Miao Zhang, Yan Meng, Chunxiao Zhu, Weihong Zhang, Hui Zhang, Zhifa Cao, Meihang Du, Zhangting Zhao, Junping Bai, Yi Han, Yang Tang, Wei Kang, Ka Fai To, Shi Jiao, Liwei An, Zhaocai Zhou   +16 more
wiley   +1 more source

A Fetal Fraction Optimized 106-Plex Digital PCR Assay for Non-Invasive Prenatal Testing of Fetal Trisomy. [PDF]

Diagnostics (Basel)
Chen S, Luan X, Cao X, Liu C, Zhang L, Shang W, Zhang Y, Yang Z, Xu C.   +8 more
europepmc   +1 more source

Screening for aneuploidy: a complex ethical issue

, 2007
Tuohey, John F.
core  

Differential Transcriptome Analysis of Intrauterine UPD6pat Fetuses With Distinct Phenotypes

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
Paternal uniparental disomy of chromosome 6 (UPD6pat) is associated with transient neonatal diabetes mellitus and multisystem developmental anomalies, but the mechanisms underlying its phenotypic variability remain unclear. This study integrates amniotic fluid cfRNA transcriptome analysis and molecular diagnostics, identifying 372 differentially ...
Jiahui Yu, Yan Zhang, Wenlong Shen, Jun Ying, Huanzheng Li, Xiaohua Tang, Xujun He   +6 more
wiley   +1 more source

Indication and diagnostic method selection for invasive prenatal genetic testing – review of the literature and conclusions of the Austrian consensus conference on prenatal genetic testing. [PDF]

Med Genet
Verheyen S, Pertl B, Bierbaumer S, Fazelnia C, Jauch SF, Klaritsch P, Krampl-Bettelheim E, Kühberger S, Reischer T, Reiter R, Scharnreitner I, Steiner H, Zschocke J, Pfeifer M.   +13 more
europepmc   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Morphogen Gradients as Drivers of Mosaicism During Early Human Development. [PDF]

Bioessays
Acebrón SP, Hattemer J, Rausch T, De Jaime-Soguero A.   +3 more
europepmc   +1 more source

Avoidant/restrictive food intake disorder complicated by superior mesenteric artery syndrome in an adolescent male with Klinefelter syndrome: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Avoidant/restrictive food intake disorder (ARFID) is characterized by restrictive or avoidant eating not driven by weight or shape concerns and is often associated with autism spectrum disorder (ASD). Superior mesenteric artery (SMA) syndrome may occur in ARFID with significant weight loss; however, overlapping gastrointestinal ...
Kohei Kamikawa, Ryohei Takada, Yuya Honda, Harue Goto, Takashi Okada   +4 more
wiley   +1 more source

Common variation in meiosis genes shapes human recombination and aneuploidy. [PDF]

Nature
Carioscia SA, Biddanda A, Starostik MR, Tang X, Hoffmann ER, Demko ZP, McCoy RC.   +6 more
europepmc   +1 more source

SEX CHROMOSOME ANEUPLOIDY: PROSPECTIVE STUDIES ON CHILDREN

, 1979

core