Results 141 to 150 of about 47,394 (257)

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source

Association between ovarian reserve and utilization of preimplantation genetic testing for aneuploidy in autologous IVF cycles. [PDF]

Hum Reprod Open
Barad DH, Darmon S, Gayete-Lafuente S, Guijarro-Baude L, Albertini DF, Patrizio P, Nicholas C, Gleicher N.   +7 more
europepmc   +1 more source

Preimplantation Genetic Testing for Families at Risk of Haemophilia: Ten‐Year Single‐Centre Experience

Haemophilia, EarlyView.
ABSTRACT Introduction Preimplantation genetic testing for monogenic diseases (PGT‐M) is a reproductive option for couples at high risk of transmitting inherited disorders. We report a ten‐year single‐centre PGT‐M experience in families at risk of hemophilia.
Mimosa Mortarino, Isabella Garagiola, Valeria Nicotra, Alessandra Riccaboni, Cristina Guarneri, Edgardo Somigliana, Flora Peyvandi   +6 more
wiley   +1 more source

Aneuploidy in exfoliated buccal cells: mechanisms, methods, and future perspectives. [PDF]

Mutagenesis
Kirsch-Volders M, Mišík M, Fenech M.
europepmc   +1 more source

Circadian Deregulation in Multiple Myeloma: BMAL1/CLOCK Expression Patterns and Diagnostic Performance

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak, Mustafa Ertan Ay, Anıl Tombak, Kenan Çevik, Özlem İzci Ay, Tuba Kabasakal, Mehmet Emin Erdal   +6 more
wiley   +1 more source

Application of non-invasive preimplantation genetic screening for aneuploidy through spent embryo culture media analysis at 48 and 54 hours after embryo cleavage. [PDF]

Br J Biomed Sci
Satirapod C, Niransuk P, Tantanavipas S, Sensorn I, Chantratita W, Trachoo O.   +5 more
europepmc   +1 more source

Recent advances in the genomics of sugarcane (Saccharum)

Journal of Integrative Plant Biology, EarlyView.
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang, Qin Zhang, Qiutao Xu, Han Zhao, Zhen Li, Jisen Zhang   +5 more
wiley   +1 more source

A FISH-Based Three-Tier Classification of Chromosome 3 Alterations in Clear Cell Renal Cell Carcinoma: Diagnostic and Prognostic Implications Utility. [PDF]

Cancers (Basel)
Deng S, Ye T, Zhang L, Zhou L, Liu Y, Che Y, Dong L, Wang C, Yang X.   +8 more
europepmc   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

What's in a Prompt? Assignment Prompt Cues Influence Data Analysis, Critique, and Inclusion of Follow-up Experiments. [PDF]

CBE Life Sci Educ
Zak S, McDonnell L, Tour E.
europepmc   +1 more source