Results 131 to 140 of about 47,394 (257)
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang +7 more
wiley +1 more source
Misdiagnosis of different types of aneuploidy in preimplantation genetic testing (PGT): a systematic review and meta-analysis. [PDF]
Jiang W +23 more
europepmc +1 more source
Combinatorial effects of multiple genes contribute to beneficial aneuploidy phenotypes. [PDF]
Koller MS +4 more
europepmc +1 more source
Biogenesis of TNF‐α‐insights into proteostasis and inflammation
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar +3 more
wiley +1 more source
Recurrent Hodgkin's Lymphoma Detected Using Abnormal NIPT in Pregnancy: A Case Report and Literature Review. [PDF]
Szlek C +8 more
europepmc +1 more source
Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril +2 more
wiley +1 more source
Abnormal Endocytosis Resulting from Imbalanced Proteomic Doses in Human Aneuploid Embryos. [PDF]
Duan R, Liang X, Yang Y, Guo J.
europepmc +1 more source
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari +7 more
wiley +1 more source
Meiotic gene variants contribute to recurrent blastulation failure. [PDF]
Chen X +19 more
europepmc +1 more source

