Results 161 to 170 of about 54,677 (265)

Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos. [PDF]

Aging (Albany NY)
Reig A, Seli E.
europepmc   +1 more source

Cross‐Ancestry Polygenic Prediction: Comparing Methods and Assessing Transferability Across Traits

Genetic Epidemiology, Volume 50, Issue 1, February 2026.
ABSTRACT Accurate prediction of disease risk and other complex traits across different populations is essential for clinical and research purposes. However, genetic differences among ancestries, such as allelic frequencies and genetic architecture, can affect the performance of polygenic risk score (PGS) methods in cross‐ancestry prediction. To address
Md. Moksedul Momin, Xuan Zhou, Muktar Ahmed, Elina Hyppönen, Beben Benyamin, S. Hong Lee   +5 more
wiley   +1 more source

Integrative Omics Analysis Reveals the Potential Value of CEACAM6 in Pan‐Gastrointestinal Cancers

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Expression of CEACAM6 in spatial transcriptomic of colorectal cancer with liver metastases. (A) Predicted cell types mapping on colorectal cancer tissue slice; (B) Spatial distribution of CEACAM6; (C) Spatial distribution of malignant region, mixed region and normal region; (D) The difference expression of CEACAM6 in malignant region, mixed region and ...
Liying Jin, Changjuan Tao, Zhiyong Pan, Peng Zhang   +3 more
wiley   +1 more source

Rapid gain and loss of a chromosome drives key morphology and virulence phenotypes in the fungal pathogen Histoplasma. [PDF]

PLoS Biol
Heater S, Voorhies M, Rodriguez RA, English BC, Sil A.   +4 more
europepmc   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, Volume 158, Issue 3, Page 642-655, 1 February 2026.
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

Drivers of achiasmatic meiosis: sexual antagonism versus heteromorphy-dependent aneuploidy across sex-chromosome divergence. [PDF]

G3 (Bethesda)
Barboza A, Blackmon H.
europepmc   +1 more source

Implications of aneuploidy for stem cell biology and brain therapeutics [PDF]

, 2012
Sylvie Devalle, Rafaela Sartore, Bruna S. Paulsen, Helena L. Borges, Rodrigo A. P. Martins, Stevens K. Rehen   +5 more
openalex   +1 more source

Cytogenomic Abnormalities in Children With Acute Lymphoblastic Leukemia From Western Mexico: A Single‐Center Fluorescence In Situ Hybridization‐Based Study

eJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Introduction In Mexico, the 5‐year overall survival (OS) rate for pediatric acute lymphoblastic leukemia (ALL) ranges from 45% to 85%, markedly lower than the ∼90% reported in high‐income countries, where cytogenomic testing is essential for accurate risk stratification and therapeutic decision‐making.
Rosa María González Arreola, María Teresa Magaña Torres, Ma. Guadalupe Domínguez Quezada, Janet Margarita Soto Padilla, José Luis Toro Castro, Beatriz Kazuko De la Herrán Arita, Alicia Gutiérrez Méndez, Hugo Antonio Romo Rubio, Juan Ramón González García   +8 more
wiley   +1 more source

Response Prediction of Chemoradiotherapy for Rectal Cancer Using Rapid Semi-Automated Flow Cytometry. [PDF]

Cancers (Basel)
Amagai H, Hayano K, Shioyama T, Suzuki A, Ohira G, Maruyama T, Tochigi T, Okada K, Arasawa T, Sekino N, Mizumachi R, Hirasawa S, Uesato M, Maruyama M, Kurata Y, Hirata A, Matsubara H.   +16 more
europepmc   +1 more source

Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children [PDF]

, 2009
Lucia Migliore, Francesca Migheli, Fabio Coppedè   +2 more
openalex   +1 more source