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Simultaneous analysis of coumarin derivatives in extracts of Radix Angelicae pubescentis (Duhuo) by HPLC-DAD-ESI-MSn technique

Anal. Methods, 2014
Radix Angelicae pubescentis (Duhuo) is a traditional Chinese herbal medicine (TCM) used for the treatment of rheumatic diseases.
Bin Wang   +4 more
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Identify nature N-acylethanolamide-hydrolyzing acid amide (NAAA) inhibitor: effect of Angelicae Pubescentis Radix on anti-inflammation

China Journal of Chinese Materia Medica, 2011
Objective To investigate the effect of Angelicae Pubescentis Radix (APR) on the activity of endocannabinoid hydrolase and N-acylethanolamine-hydrolyzing acid amidase (NAAA), and to demonstrate the mechanism of anti-inflammatory effect of APR by in vitro lipopolysaccharide (LPS)-induced inflammation model.
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[In situ rats single pass perfusion intestinal absorption of the effectivein components in Radix Angelicae Pubescentis].

Yao xue xue bao = Acta pharmaceutica Sinica, 2009
In order to study the intestinal absorption behaviors of three active constituents, columbianetin acetate, osthole and columbianadin in Radix Angelicae Pubescentis extracts, in situ rat single pass intestine perfusion (SPIP) was carried out by the perfusion solution of the extract I containing less than 10% total coumarins. The absorption of extract II
Ya-Na, Wu, Li-Biao, Luan
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[Identification of Chinese traditional medicine Angelicae Pubescentis Radix from different places by fourier transform infrared spectrometry].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014
Common and variation peak rates were calculated as dual-index for drug samples based on the infrared spectrogram of Angelicae Pubescentis Radix samples from different places. The results indicated that the common peak rates of 4 samples from Sichuan province, 2 samples from Gansu province, and 2 samples from Hubei province were higher than 73% , 79. 5%
Ye, Zhou   +5 more
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Fast and accurate discrimination analysis of Angelicae Pubescentis Radix using non-targeted analytical profiles images and two-dimensional convolution neural network

Journal of Chromatography A
This study developed an effective approach for discriminating geographical origins of Duhuo samples using non-targeted UPLC chromatograms and UV-Vis spectrogram images combined with a two-dimensional convolution neural network (2D-CNN). For comparison, four machine learning methods-extreme gradient boosting (XGBoost), random forest (RF), partial least ...
Yue, Huang   +4 more
openaire   +2 more sources

Fabrication of a biochar-doped monolithic adsorbent and its application for the extraction and determination of coumarins from Angelicae Pubescentis Radix

Journal of Chromatography A
A monolithic adsorbent was designed aiming to the structure of osthole and columbianadin, and fabricated using diallyl phthalate as the monomer and ethylene dimethacrylate as the crosslinker with the addition of bamboo biochar, via polymerization reaction in a stainless-steel tube. The prepared composite adsorbent packed in the tube was used as a solid-
Changqing Yu   +3 more
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A distinct new microscopic feature for identification of the crude drug of Radix Angelicae Pubescentis

2010
Objective: In order for effective authentication of Radix Angelicae Pubescentis and to establish a basis of the herb standardization,the detailed morphological and microscopic characteristics were investigated.Methods: Samples were collected from the representative producing areas of China;the conventional pharmacognostic techniques were adopted for ...
Tong, Y   +4 more
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Microwave-assisted extraction coupled with counter-current chromatography and preparative liquid chromatography for the preparation of six furocoumarins from Angelica Pubescentis Radix

Separation and Purification Technology, 2015
Abstract An efficient separation and purification method by microwave-assisted extraction coupled with counter-current chromatography and preparative liquid chromatography was developed. The extracts obtained from microwave-assisted extraction were rapid separated with counter-current chromatography, and then the fractions were further purified with ...
Geng-jin-sheng Cheng   +2 more
openaire   +1 more source

[Identify nature N-acylethanolamide-hydrolyzing acid amide (NAAA) inhibitor: effect of angelicae pubescentis radix on anti-inflammation].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012
To investigate the effect of Angelicae Pubescentis Radix (APR) on the activity of endocannabinoid hydrolase and N-acylethanolamine-hydrolyzing acid amidase (NAAA), and to demonstrate the mechanism of anti-inflammatory effect of APR by in vitro lipopolysaccharide (LPS)-induced inflammation model.APR essential oil was extracted by steam distillation, and
Wenchang, Sun   +5 more
openaire   +1 more source

The vasorelaxation effect of osthole, derived from radix angelicae pubescentis, in porcine coronary artery

2010
Radix Angelicae Pubescentis is a traditional Chinese medicine used to treat thrombosis. Osthole, a coumarin from Angelica pubescens, possesses antiarrhythmic activity. The vascular effects of Angelica pubescens extract (APE) and osthole, as well as their underlying signaling pathways, were investigated in isolated porcine coronary artery rings ...
Keung, WYW   +5 more
openaire   +1 more source

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