Results 101 to 110 of about 20,679 (232)
Emergency Department Triage Nurses' Scope of Practice: An Observational Study
ABSTRACT Aim To explore emergency department triage nurses' scope of practice and activities related to their triage role and management of patients located in emergency department waiting areas. Design Exploratory, descriptive, observational study using naturalistic decision making.
Julie Considine +8 more
wiley +1 more source
Life-threatening angioedema induced by angiotensin-converting enzyme inhibitor: two case reports
Background. Angioedema is a rare but potentially very serious complication of treatment with angiotensin converting enzyme inhibitors (ACEI). Angioedema is due to the accumulation of bradykinin, because angiotensin converting enzyme is the key enzyme for
Erik Rupnik +3 more
doaj
In this two‐center retrospective series of eight patients with localized PDGFRA‐mutant gastric GIST treated with preoperative avapritinib, therapy produced substantial antitumor activity, including tumor reduction in 7 of 8 patients and complete or near‐complete pathologic response in all resected patients.
Tannaz Ranjbarian +8 more
wiley +1 more source
Sustained Effectiveness of Lanadelumab in Preventing Hereditary Angioedema Attacks: The ENABLE Study
ABSTRACT Background Lanadelumab has been approved for hereditary angioedema (HAE) long‐term prophylaxis since 2018. The Phase 4, prospective ENABLE Study (NCT04130191) evaluated the long‐term effectiveness and safety of lanadelumab in clinical practice across Europe and the Middle East.
Andrea Zanichelli +15 more
wiley +1 more source
Berotralstat Tolerability and Effectiveness in Hereditary Angioedema: Berolife Study Results
ABSTRACT Background Berotralstat is a first‐line once‐daily oral prophylactic treatment for hereditary angioedema (HAE). Berolife was designed to evaluate the tolerability and effectiveness of berotralstat in real‐world conditions. Methods Berolife is an open‐label, multicenter, observational study conducted in France from September 2021 to January ...
Delphine Gobert +26 more
wiley +1 more source
ABSTRACT Drug hypersensitivity reactions (DHRs) are a global health concern and remain challenging to investigate owing to the heterogeneity of endotypes and phenotypes, as well as the lack of standardized biomarkers. Until recently, strict drug avoidance was the only management strategy for severe DHRs.
Ana Maria Copaescu +13 more
wiley +1 more source
Daily supplementation with Ziziphus jujube fruit improved liver enzymes, lipid profile, and hepatic steatosis in patients with non‐alcoholic fatty liver disease (NAFLD), potentially through its antioxidant, anti‐inflammatory, and lipid‐modulating properties.
Ronak Borzooei +4 more
wiley +1 more source
ABSTRACT Background and Aims Urticaria is a condition which can impair the quality of life of affected individuals. There is a lack of recent studies on the burden of this disease in the Middle East and North Africa (MENA) region. This article reported the incidence, prevalence, and disability‐adjusted life years (DALYs) of urticaria from 1990 to 2021 ...
Amir Sajad Bagheryan +6 more
wiley +1 more source
Factors Influencing Self‐Reported Health in Puerto Rican Populations: A Systematic Review
ABSTRACT Background and Aims Puerto Ricans experience disproportionate chronic disease burden, structural barriers to care, and disparities in health outcomes. Self‐reported health is a validated indicator of morbidity, mortality, and healthcare utilization, yet its determinants in Puerto Rican populations remain insufficiently synthesized. This review
Anthony Vincent Razzano
wiley +1 more source
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
wiley +1 more source

