Results 11 to 20 of about 49,086 (290)

Acquired angioedema [PDF]

Allergy, Asthma & Clinical Immunology, 2010
Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact-kinin system.
M. Cicardi, A. Zanichelli
openaire   +4 more sources

Attenuated androgen discontinuation in patients with hereditary angioedema: a commented case series

Allergy, Asthma & Clinical Immunology, 2022
Background Hereditary angioedema (HAE) is characterized by potentially severe and life-threatening attacks of localized swelling. Prophylactic therapies are available, including attenuated androgens. Efficacy of attenuated androgens has not been assessed
Marcus Maurer, Markus Magerl, Emel Aygören-Pürsün, Konrad Bork, Henriette Farkas, Hilary Longhurst, Sorena Kiani‑Alikhan, Laurence Bouillet, Isabelle Boccon-Gibod, Mauro Cancian, Andrea Zanichelli, David Launay   +11 more
doaj   +1 more source

Late Hypersensitivity Reactions to the BNT162b2 SARS-CoV-2 Vaccine Are Linked to Delayed Skin Sensitization and Prior Exposure to Hyaluronic Acid

Life, 2022
Background: Late hypersensitivity reactions (HSRs) to the BNT162b2-vaccine have raised concerns regarding its safety, particularly as further immunizations are required. The yield of skin testing with the BNT162b2v is unclear, as well as the risk factors
Ramit Maoz-Segal, Ronen Shavit, Mona Iancovici Kidon, Irena Offengenden, Diti Machnes-Maayan, Yulia Lifshitz-Tunitsky, Stanley Niznik, Nancy Agmon-Levin   +7 more
doaj   +1 more source

The characteristics of upper airway edema in hereditary and acquired angioedema with C1‐inhibitor deficiency

Clinical and Translational Allergy, 2021
Background Angioedemas localized in the upper airway are potentially life threatening, and without proper treatment, they may lead to death by suffocation. Upper airway edemas (UAE) in bradykinin‐mediated angioedemas can even be the first symptoms of the
Zsuzsanna Balla, Noémi Andrási, Zsófia Pólai, Beáta Visy, Ibolya Czaller, György Temesszentandrási, Dorottya Csuka, Lilian Varga, Henriette Farkas   +8 more
doaj   +1 more source

Hypersensitivity reactions amongst Hungarian Patients with Hereditary Angioedema due to C1-Inhibitor Deficiency

World Allergy Organization Journal, 2023
Background: In hereditary angioedema (HAE) due to C1-inhibitor deficiency (C1-INH-HAE), bradykinin-mediated submucosal and/or subcutaneous angioedema dominates the clinical picture.
Hanga Réka Horváth, MD, Dávid Szilágyi, MD, Noémi Andrási, MD, Zsuzsanna Balla, MD, PhD, Beáta Visy, MD, PhD, Henriette Farkas, MD, PhD, DSc   +5 more
doaj   +1 more source

C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency

Orphanet Journal of Rare Diseases, 2023
Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods. Our aim
Zsofia Polai, Erika Kajdacsi, Laszlo Cervenak, Zsuzsanna Balla, Szabolcs Benedek, Lilian Varga, Henriette Farkas   +6 more
doaj   +1 more source

Patient‐physician interactions in hereditary angioedema—Key learnings from the coronavirus disease 2019 pandemic

Clinical and Translational Allergy, 2023
Background The coronavirus disease pandemic and its containing measures have caused concerns for patients with hereditary angioedema (HAE) and their treating physicians.
Marcus Maurer, Thomas Buttgereit, Markus Magerl, Kathrin Schön, Zsusanna Balla, Henriette Farkas   +5 more
doaj   +1 more source

Combination therapy with omalizumab and an immune-suppressive agent for resistant chronic spontaneous rrticaria - A real-life experience

World Allergy Organization Journal, 2020
Background: Chronic Spontaneous Urticaria (CSU) is a relatively common immune mediated disease that can be effectively treated nowadays. Nevertheless, for some patients remission cannot be achieved following current treatment recommendations, defined as ...
Ramit Maoz-Segal, Tanya Levy, Soad Haj-Yahia, Irena Offengenden, Mona Iancovich-Kidon, Nancy Agmon-Levin   +5 more
doaj   +1 more source

Risk of angioedema following invasive or surgical procedures in HAE type I and II : the natural history [PDF]

, 2013
Background: Hereditary angioedema (HAE), caused by deficiency in C1-inhibitor (C1-INH), leads to unpredictable edema of subcutaneous tissues with potentially fatal complications.
Aygören-Pürsün, Emel, Klingebiel, Thomas, Kreuz, Wolfhart, Martinez Saguer, Inmaculada, Schwabe, Dirk   +4 more
core   +1 more source

Application of a dried blood spot based proteomic and genetic assay for diagnosing hereditary angioedema

Clinical and Translational Allergy, 2023
Background Hereditary angioedema (HAE) with C1‐inhibitor deficiency (C1‐INH‐HAE) is a rare disease caused by low level (type I) or dysfunction (type II) of the C1‐inhibitor protein with subsequent reduction of certain complement protein levels.
Marius‐Ionuţ Iuraşcu, Zsuzsanna Balla, Catarina Pereira, Noémi Andrási, Lilian Varga, Dorottya Csuka, Ágnes Szilágyi, Kornelia Tripolszki, Suliman Khan, Iuliana Susnea, Peter Bauer, Claudia Cozma, Henriette Farkas   +12 more
doaj   +1 more source