Results 71 to 80 of about 20,679 (232)
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Background: Bradykinin (BK), a 9–amino acid peptide, is a key mediator responsible for angioedema attacks in hereditary angioedema due to C1INH deficiency (HAE-C1INH).
Jinguo Chen, MD +7 more
doaj +1 more source
This study examined whether antibiotic use altered the risk of infant allergic disease within a maternal prebiotics supplementation trial. Intrapartum antibiotics were maternal antibiotics administered during childbirth, from the onset of labour or induction until 1‐h before delivery.
Summer V. M. Walker +10 more
wiley +1 more source
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source
Institutional Incidence of Severe tPA-Induced Angioedema in Ischemic Cerebral Vascular Accidents
Introduction. Tissue plasminogen activator (tPA) is commonly used in ischemic cerebral vascular accidents (CVAs). tPA is generally well tolerated; however, orolingual angioedema is a well-documented adverse effect. Angioedema is generally mild, transient,
Matthew Sczepanski, Paul Bozyk
doaj +1 more source
Hereditary angioedema is an autosomal dominant disease characterized by recurrent angioedema attacks with the involvement of multiple organs. The disease is unknown to many health professionals and is therefore underdiagnosed.
Pedro Giavina-Bianchi +26 more
doaj +1 more source
Bilateral infantile Frey syndrome mimicking food allergy: A case report
Pediatric Investigation, EarlyView.
Yuki Ohara, Mayumi Fujita, Chisato Inuo
wiley +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
Hereditary angioedema — a rare disease caused by a congenital deficiency of C1-inhibitor. Clinical manifestations of the disease — recurrent episodes of angioedema, which manifest in childhood or adolescence, more often localized in the subcutaneous ...
A.P. Volokha
doaj +1 more source
This observational analysis of a consecutive tertiary‐care cohort included 70 patients with walnut allergy and 44 patients with hazelnut allergy. Clinical severity was classified as mild, moderate, or severe. Hazelnut and walnut allergy severity was better captured by molecule‐specific IgE profiles than by undifferentiated seed storage protein ...
Danilo Villalta +14 more
wiley +1 more source

