Results 111 to 120 of about 813,397 (344)

Isolation of equine endothelial cells and life cell angiogenesis assay [PDF]

, 2014
Arterial or venous thromboses are frequent clinical complications with the risk of fatal progression. Recent studies suggest the disruption of angiogenesis in the course of thrombus resolution as the underlying pathomechanism.
Dietze, Kathrin, Fuhrmann-Selter, Tania, Hopperdietzel, Carsten, Kaessmeyer, Sabine, Plendl, Johanna, Slosarek, Ilka   +5 more
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation

Frontiers in Oncology, 2018
Advancements in the early detection of cancer coupled with improved surgery, radiotherapy, and adjuvant therapy led to substantial increase in patient survival. Nevertheless, cancer metastasis is the leading cause of death in several cancer patients. The
Amit S. Yadav, Poonam R. Pandey, Ramesh Butti, N. N. V. Radharani, Shamayita Roy, Shaileshkumar R. Bhalara, Mahadeo Gorain, Gopal C. Kundu, Dhiraj Kumar, Dhiraj Kumar   +9 more
doaj   +1 more source

Electrochemical sensing of angiogenin induced endothelial nitric oxide synthase activity [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Chang, SI, Chung, HM, Kang, DK, O'Hare, D, Trouillon, R   +5 more
core  

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Expression and purification of bioactive, low-endotoxin recombinant human vitronectin

BioTechniques, 2014
The secreted adhesive glycoprotein vitronectin (VTN) is a multifunctional component of plasma and the extracellular matrix. A high-yielding, inexpensive, low endotoxin source of bioactive recombinant human vitronectin (rhVTN) is highly desirable for in ...
Michael M. Halford, Yi-Chao He, Steven A. Stacker   +2 more
doaj   +1 more source

Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression

, 2016
Angiogenesis involves the formation of new blood vessels by sprouting or splitting of existing blood vessels. During sprouting, a highly motile type of endothelial cell, called the tip cell, migrates from the blood vessels followed by stalk cells, an ...
Dallinga, Marchien G., Klaassen, Ingeborg, Merks, Roeland M. H., Palm, Margriet M., Schlingemann, Reinier O., van Dijk, Erik   +5 more
core   +3 more sources

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Cripto-1 and Cripto-3 differential expression pattern in human placenta, umbilical cord and fetal tissues suggests new functions for these proteins

Scientific Reports
Cripto-1 (CR1) is an oncofetal protein involved in EGF/TGFβ signal transduction, with important functions in development, stem cell biology and cancer. Its homolog, Cripto-3 (CR3), is almost identical, with the exception of six (out of 188) amino acids ...
Josune García-Sanmartín, Judit Narro-Íñiguez, María José Puente, Frank Cuttitta, Alfredo Martínez   +4 more
doaj   +1 more source

Inhibition of Tumor Growth and Angiogenesis by Soluble EphB4

Neoplasia: An International Journal for Oncology Research, 2004
EphB receptors and their ephrinB ligands play a key role in the formation of a regular vascular system. Recent studies have also shown the involvement of Eph/ephrin interactions in malignant tumor progression and angiogenesis.
Georg Martiny-Baron, Thomas Korff, Florence Schaffner, Norbert Esser, Stefan Eggstein, Dieter Marme, Hellmut G. Augustin   +6 more
doaj   +1 more source