Results 101 to 110 of about 354,639 (240)

Vascular Endothelial Growth Factor Concentration in Brain of Rat Treated with Anaerobic Exercises [PDF]

, 2015
Anaerobic exercise is a high-intensity exercise that needs quick energy supplies obtained in a very short time. However, this exercise may result in tissue hypoxia which is characterized by the increase of HIF-1α concentration.
Ardi, Y. (Yuliana), Flora, R. (Rostika), Juliansyah, R. A. (Rahmad), Slamet, S. (Samwilson), Sorena, E. (Esti), Wati, R. (Roslina), Wena, S. (Syokuma), Zulkarnain, M. (Muhammad)   +7 more
core  

Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes [PDF]

, 2003
Background - Further to promoting angiogenesis, cell therapy may be an approach for cardiac regeneration. Recent studies suggest that progenitor cells can transdifferentiate into other lineages. However, the transdifferentiation potential of endothelial
Aicher, A, Badorff, C, Brandes, RP, Busse, R, Dimmeler, S, Fleming, I, Popp, R, Rupp, S, Urbich, C, Zeiher, AM   +9 more
core   +1 more source

Verteporfin inhibits growth of human glioma in vitro without light activation

Scientific Reports, 2017
Verteporfin (VP), a light-activated drug used in photodynamic therapy for the treatment of choroidal neovascular membranes, has also been shown to be an effective inhibitor of malignant cells.
Ahmad Al-Moujahed, Katarzyna Brodowska, Tomasz P. Stryjewski, Nikolaos E. Efstathiou, Ioannis Vasilikos, Joanna Cichy, Joan W. Miller, Evangelos Gragoudas, Demetrios G. Vavvas   +8 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Role of mTOR signaling in tumor microenvironment. An overview [PDF]

, 2018
The mammalian target of rapamycin (mTOR) pathway regulates major processes by integrating a variety of exogenous cues, including diverse environmental inputs in the tumor microenvironment (TME).
Bazzichetto, Chiara, Bria, Emilio, Ciuffreda, L., Cognetti, F., COGNETTI, FRANCESCO, Conciatori, Fabiana, Falcone, I., Milella, M., Pilotto, Sara   +8 more
core   +2 more sources

Synthesis of a Novel Thermoresponsive S53P4 Bioactive Glass Extract–Poloxamer 407 Injectable Hydrogels: Assessment of Biocompatibility and Antimicrobial Properties

Advanced Engineering Materials, EarlyView.
This study investigates innovative thermoreversible hydrogels derived from S53P4 bioactive glass extracts to aid in the healing of infected diabetic foot wounds. These injectable gels, which gel at body temperature, release beneficial ions and remain stable over time.
Marian G. Vargas Guerrero, Adrian Stiller, Alex Nygård, Matej Krivulka, Lars Galema, Erwin Peters, Jimmy Lucchesi, Peter Uppstu, Leena Hupa, Jacobus J. C. Arts   +9 more
wiley   +1 more source

The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization [PDF]

, 2011
Angiogenesis, or neovascularization, is a finely balanced process controlled by pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a major pro-angiogenic factor, whereas pigment epithelial-derived factor (PEDF) is the most ...
Crawford, Ross, Fan, Wei, Xiao, Yin
core   +2 more sources

Angiogenesis [PDF]

BioMed Research International, 2015
Qiang Zhao, Zongjin Li
openaire   +2 more sources

From monocyte‐derived macrophages to resident macrophages—how metabolism leads their way in cancer

Molecular Oncology
Macrophages are innate immune cells that play key roles during both homeostasis and disease. Depending on the microenvironmental cues sensed in different tissues, macrophages are known to acquire specific phenotypes and exhibit unique features that ...
Ummi Ammarah, Andreia Pereira‐Nunes, Marcello Delfini, Massimiliano Mazzone   +3 more
doaj   +1 more source

Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease

EMBO Molecular Medicine, 2014
The endothelium is the orchestral conductor of blood vessel function. Pathological blood vessel formation (a process termed pathological angiogenesis) or the inability of endothelial cells (ECs) to perform their physiological function (a condition known ...
Jermaine Goveia, Peter Stapor, Peter Carmeliet   +2 more
doaj   +1 more source