Results 261 to 270 of about 618,864 (305)
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Annual Review of Medicine, 1984
Angiogenesis inhibitors for the treatment of cancer have now been approved by the Food and Drug Administration in the United States, and in 28 other countries including China. Clinical application of this new class of drugs is informed by certain principles from angiogenesis research.
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Angiogenesis inhibitors for the treatment of cancer have now been approved by the Food and Drug Administration in the United States, and in 28 other countries including China. Clinical application of this new class of drugs is informed by certain principles from angiogenesis research.
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Angiogenesis and anti-angiogenesis in hepatocellular carcinoma
Cancer Treatment Reviews, 2006Experimental and clinical data indicate that in human hepatocellular carcinoma (HCC) tumor progression is associated with angiogenesis and that an increase in microvascular density is associated with a poor prognosis. This review summarizes the literature concerning the relationship between angiogenesis and progression in HCC.
RIBATTI, Domenico +4 more
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Angiogenesis-dependent diseases and angiogenesis therapy
Pathology & Oncology Research, 2001The discovery of the molecular mechanisms of physiological vasculogenesis and pathological angiogenesis helped to recognize two classes of diseases: one where the therapeutic angiogenesis can repair the tissue damages (arteriosclerosis, myocardial infarction, limb ischemia) and the other one where inhibition of pathological angiogenesis can cure the ...
J, Tímár +4 more
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Pancreatology, 2010
The rapid growth of cancer cells, such as the case with pancreatic cancer cells, requires new blood vessel growth to sustain tumor viability. In fact, angiogenesis has been found to be closely correlated with rapid tumor growth and a poorer prognosis in pancreatic cancer.
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The rapid growth of cancer cells, such as the case with pancreatic cancer cells, requires new blood vessel growth to sustain tumor viability. In fact, angiogenesis has been found to be closely correlated with rapid tumor growth and a poorer prognosis in pancreatic cancer.
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Atherosclerosis Supplements, 2003
Angiogenesis requires the elaboration of endothelium-derived nitric oxide (NO). Angiogenic factors induce the release of NO from endothelial cells, which mediates a multiplicity of processes involved in angiogenesis. These NO-modulated processes include endothelial cell survival, proliferation, migration, and interaction with the extracellular matrix ...
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Angiogenesis requires the elaboration of endothelium-derived nitric oxide (NO). Angiogenic factors induce the release of NO from endothelial cells, which mediates a multiplicity of processes involved in angiogenesis. These NO-modulated processes include endothelial cell survival, proliferation, migration, and interaction with the extracellular matrix ...
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Angiogenesis in transgenic models of multistep angiogenesis
2004The histopathology and the epidemiology of human cancers, as well as studies of animal models of tumorigenesis, have led to a widely accepted notion that multiple genetic and epigenetic changes have to accumulate for progression to malignancy. Formation of new blood vessels (tumor angiogenesis) has been recognized, in addition to proliferative ...
Radovanovic I, D'Angelo MG, Aguzzi A
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2015
Angiogenesis plays a pivotal role in malignant, ischemic, inflammatory, infectious and immune disorders. The increasing molecular understanding of angiogenic processes fostered the development of strategies to induce or inhibit angiogenesis for therapeutic purposes.
H, Büning, U T, Hacker
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Angiogenesis plays a pivotal role in malignant, ischemic, inflammatory, infectious and immune disorders. The increasing molecular understanding of angiogenic processes fostered the development of strategies to induce or inhibit angiogenesis for therapeutic purposes.
H, Büning, U T, Hacker
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Angiogenesis and angiogenesis inhibition: An overview
1997The study of angiogenesis attracts investigators from many different fields who find that regulation of blood vessel growth underlies a wide spectrum of biologic processes. These include reproduction, development, repair, angiogenic diseases, and cancer (Folkman, 1995).
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2002
Epithelial ovarian cancer constitutes approximately 85% of all ovarian malignancies. The lack of overt symptoms and good screening strategies precludes early diagnosis and thus greater than 70% of patients present with extensive local disease and peritoneal spread (1).
Gregory J, Sieczkiewicz +2 more
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Epithelial ovarian cancer constitutes approximately 85% of all ovarian malignancies. The lack of overt symptoms and good screening strategies precludes early diagnosis and thus greater than 70% of patients present with extensive local disease and peritoneal spread (1).
Gregory J, Sieczkiewicz +2 more
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2017
Angiogenesis is a dynamic and energy-consuming process, requiring endothelial cells to switch from a quiescent state to a migratory and proliferative phenotype in order to support the formation of new blood vessels. Despite their proximity to oxygenated blood endothelial cells are adept at utilizing glycolysis as an energy source to the detriment of ...
Raluca, Marcu +2 more
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Angiogenesis is a dynamic and energy-consuming process, requiring endothelial cells to switch from a quiescent state to a migratory and proliferative phenotype in order to support the formation of new blood vessels. Despite their proximity to oxygenated blood endothelial cells are adept at utilizing glycolysis as an energy source to the detriment of ...
Raluca, Marcu +2 more
openaire +2 more sources