Results 271 to 280 of about 618,864 (305)
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Current Opinion in Nephrology and Hypertension, 2000
Research during the past few years has contributed vastly to a better understanding of fibrosis and angiogenesis. Although studies to understand the molecular processes associated with fibrosis and angiogenesis were performed independently of each other, some common parallels have emerged.
R, Kalluri, V P, Sukhatme
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Research during the past few years has contributed vastly to a better understanding of fibrosis and angiogenesis. Although studies to understand the molecular processes associated with fibrosis and angiogenesis were performed independently of each other, some common parallels have emerged.
R, Kalluri, V P, Sukhatme
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Nature, 1997
After the developing embryo has formed a primary vascular plexus by a process termed vasculogenesis, further blood vessels are generated by both sprouting and non-sprouting angiogenesis, which are progressively pruned and remodelled into a functional adult circulatory system.
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After the developing embryo has formed a primary vascular plexus by a process termed vasculogenesis, further blood vessels are generated by both sprouting and non-sprouting angiogenesis, which are progressively pruned and remodelled into a functional adult circulatory system.
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New England Journal of Medicine, 1981
In this issue of the Journal, Chodak and his co-workers1 report that urine from patients with carcinomas of transitional epithelium induced greater mobilization of cultured capillary endothelium than did urine from a variety of controls. For a full appreciation of these results, a brief outline of previous observations related to this area of research ...
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In this issue of the Journal, Chodak and his co-workers1 report that urine from patients with carcinomas of transitional epithelium induced greater mobilization of cultured capillary endothelium than did urine from a variety of controls. For a full appreciation of these results, a brief outline of previous observations related to this area of research ...
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Blood, 2011
In this issue of Blood, Singh and colleagues identify HMG-CoA reductase-dependent farnesylation of Rac-1 as critical for 15(S)-HETE-induced angiogenesis. These findings establish a novel link between eicosanoid and cholesterol metabolism with important biologic and therapeutic implications for angiogenesis.
Lalitha, Nayak, Mukesh K, Jain
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In this issue of Blood, Singh and colleagues identify HMG-CoA reductase-dependent farnesylation of Rac-1 as critical for 15(S)-HETE-induced angiogenesis. These findings establish a novel link between eicosanoid and cholesterol metabolism with important biologic and therapeutic implications for angiogenesis.
Lalitha, Nayak, Mukesh K, Jain
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Archives of Surgery, 1993
We have proposed the term "therapeutic angiogenesis" to describe the induction or stimulation of neovascularization for the treatment or prevention of pathological clinical situations characterized by local hypovascularity. Evidence also shows that "clinically normal" healing and tissue regeneration can be improved or accelerated by therapeutic ...
M, Höckel +4 more
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We have proposed the term "therapeutic angiogenesis" to describe the induction or stimulation of neovascularization for the treatment or prevention of pathological clinical situations characterized by local hypovascularity. Evidence also shows that "clinically normal" healing and tissue regeneration can be improved or accelerated by therapeutic ...
M, Höckel +4 more
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Hypercholesterolemia and angiogenesis
The American Journal of Cardiology, 1993Hypercholesterolemia is associated with endothelial cell dysfunction, which may be partly related to an accumulation of toxic lipoprotein degradation products in artery walls. Oxidized low-density lipoprotein and its products have been incriminated in the impairment of transmembrane signaling, a process that may alter the responsiveness of endothelial ...
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Biochemical Society Transactions, 2011
The PPAR (peroxisome-proliferator-activated receptor) family consists of three ligand-activated nuclear receptors: PPARα, PPARβ/δ and PPARγ. These PPARs have important roles in the regulation of glucose and fatty acid metabolism, cell differentiation and immune function, but were also found to be expressed in endothelial cells in the late 1990s.
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The PPAR (peroxisome-proliferator-activated receptor) family consists of three ligand-activated nuclear receptors: PPARα, PPARβ/δ and PPARγ. These PPARs have important roles in the regulation of glucose and fatty acid metabolism, cell differentiation and immune function, but were also found to be expressed in endothelial cells in the late 1990s.
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Biochemistry (Moscow), 2008
Tissue activity of angiogenesis depends on the balance of many stimulating or inhibiting factors. The key signaling system that regulates proliferation and migration of endothelial cells forming the basis of any vessel are vascular endothelium growth factors (VEGF) and their receptors.
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Tissue activity of angiogenesis depends on the balance of many stimulating or inhibiting factors. The key signaling system that regulates proliferation and migration of endothelial cells forming the basis of any vessel are vascular endothelium growth factors (VEGF) and their receptors.
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2011
The angiogenic process is central in the pathogenesis of various diseases. The in vitro and in vivo monitoring of the neovascular process is essential for the development and evaluation of angiogenesis inhibitors or stimulators. Since no single method exists that can assess angiogenesis in a robust, reliable, and reproducible fashion, researchers often
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The angiogenic process is central in the pathogenesis of various diseases. The in vitro and in vivo monitoring of the neovascular process is essential for the development and evaluation of angiogenesis inhibitors or stimulators. Since no single method exists that can assess angiogenesis in a robust, reliable, and reproducible fashion, researchers often
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Targeting angiogenesis in oncology, ophthalmology and beyond
Nature Reviews Drug Discovery, 2023Napoleone Ferrara +2 more
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